Quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper)

This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2016

Detalles Bibliográficos
Autor principal:	Manzoor, Farzana
Otros Autores:	Islam, Ridwan
Formato:	Project report
Lenguaje:	English
Publicado:	BRAC University 2017
Materias:	Piper nigrum Antioxidants
Acceso en línea:	http://hdl.handle.net/10361/7625

id	10361-7625
record_format	dspace
spelling	10361-76252019-09-30T03:21:03Z Quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper) Manzoor, Farzana Islam, Ridwan Department of Pharmacy, BRAC University Piper nigrum Antioxidants This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2016 Cataloged from PDF version of project report. Includes bibliographical references (page 49-50). Piper nigrum Linn or pepper as more commonly known, is an essential everyday spice. Current study endeavours to assess the healing and medicinal properties that Piper nigrum exhibits, its role in traditional medicine and its application today. It is reported to possess antioxidant qualities that neutralize harmful “free radicals” in our body, many arguments are still being pointed towards its actual affectivity. In the present study, in vitro antioxidant activity of the seed extract of white pepper was evaluated by DPPH (2,2-diphenyl-1- picrylhydraziyl) free radical scavenging assay and total flavonoid and phenol content determination. In order to determine the cytotoxic effect of the extract, brine shrimp lethality test has been carried out where the LC50 value were determined and compared with the standard like vincristine sulphate. Our investigation indicates that the various fractions of the seed extract of white pepper contain high amount of phenol and flavonoid content with significant cytotoxic effect which may justify the traditional use of pepper and makes it as potential natural source in drug discovery and development. Farzana Manzoor B. Pharmacy 2017-01-19T08:50:47Z 2017-01-19T08:50:47Z 2016 2016-02 Project report ID 12146034 http://hdl.handle.net/10361/7625 en BRAC University project report are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 50 pages application/pdf BRAC University
institution	Brac University
collection	Institutional Repository
language	English
topic	Piper nigrum Antioxidants
spellingShingle	Piper nigrum Antioxidants Manzoor, Farzana Quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper)
description	This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2016
author2	Islam, Ridwan
author_facet	Islam, Ridwan Manzoor, Farzana
format	Project report
author	Manzoor, Farzana
author_sort	Manzoor, Farzana
title	Quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper)
title_short	Quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper)
title_full	Quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper)
title_fullStr	Quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper)
title_full_unstemmed	Quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper)
title_sort	quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper)
publisher	BRAC University
publishDate	2017
url	http://hdl.handle.net/10361/7625
work_keys_str_mv	AT manzoorfarzana quantificationoftotalphenolandflavonoidcontentinvitroinvestigationofantioxidantactivityandcytotoxiceffectoftheseedextractofpipernigrumlinnwhitepepper
_version_	1814307396850286592

Quantification of total phenol and flavonoid content, in vitro investigation of antioxidant activity and cytotoxic effect of the seed extract of piper nigrum linn (white pepper)

Ejemplares similares