Sea snail venom: A potential alternative to Opioid Analgesics
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.
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Brac University
2021
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10361-150062021-09-14T21:01:23Z Sea snail venom: A potential alternative to Opioid Analgesics Ahasan, Faiyaz Kabir , Md. Tanvir Department of Pharmacy, Brac University Marine Opioid Painkiller Ziconotide Conopeptide Snail Marine environment This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 66-84). The marine environment is a large and complex source for novel medicines. Conopeptides are present in sea snail venoms that have been detected to block pain by activating a separate molecular mechanism exploited by opioid painkillers. Researchers created a chemical version of the peptide by studying the conopeptide of cone snail called Conus magus. The synthetic form of the hydrophilic conopeptide 5-007-MVIIA used in the Pacific fish-hunting snail toxin, Conus magus, is ziconotide (also known as SNX-111). Intrathecal ziconotide is indeed a new, useful, and long-lasting dosage form that can be used for symptomatic relief of extreme persistent cancerous as well as non-malignant pain. It has been approved as an analgesic by the FDA (Food and Drug Administration and is currently used in the United States. The complications usually induced by opioids in pain treatment are likely to be overcome by using this analgesic agent. Faiyaz Ahasan B. Pharmacy 2021-09-14T06:37:29Z 2021-09-14T06:37:29Z 2021 2021-04 Thesis ID: 17146006 http://hdl.handle.net/10361/15006 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 84 Pages application/pdf Brac University |
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Brac University |
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Institutional Repository |
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en_US |
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Marine Opioid Painkiller Ziconotide Conopeptide Snail Marine environment |
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Marine Opioid Painkiller Ziconotide Conopeptide Snail Marine environment Ahasan, Faiyaz Sea snail venom: A potential alternative to Opioid Analgesics |
description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. |
author2 |
Kabir , Md. Tanvir |
author_facet |
Kabir , Md. Tanvir Ahasan, Faiyaz |
format |
Thesis |
author |
Ahasan, Faiyaz |
author_sort |
Ahasan, Faiyaz |
title |
Sea snail venom: A potential alternative to Opioid Analgesics |
title_short |
Sea snail venom: A potential alternative to Opioid Analgesics |
title_full |
Sea snail venom: A potential alternative to Opioid Analgesics |
title_fullStr |
Sea snail venom: A potential alternative to Opioid Analgesics |
title_full_unstemmed |
Sea snail venom: A potential alternative to Opioid Analgesics |
title_sort |
sea snail venom: a potential alternative to opioid analgesics |
publisher |
Brac University |
publishDate |
2021 |
url |
http://hdl.handle.net/10361/15006 |
work_keys_str_mv |
AT ahasanfaiyaz seasnailvenomapotentialalternativetoopioidanalgesics |
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