Protection against shigellosis caused by shigella dysenteriae serotype 4 in Guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain
This article was published in the Acta Microbiologica et Immunologica Hungarica [© 2017 Akadémiai Kiadó, Budapest] and the definite version is available at : http://doi.org/10.1556/030.64.2017.015 The Journal's website is at: http://akademiai.com/doi/abs/10.1556/030.64.2017.015
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| 言語: | English |
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© 2017 Akadémiai Kiadó
2018
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| オンライン･アクセス: | http://hdl.handle.net/10361/9432 http://doi.org/10.1556/030.64.2017.015 |
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10361-94322018-02-11T06:21:05Z Protection against shigellosis caused by shigella dysenteriae serotype 4 in Guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain Chowdhury, Fatema Moni Rahman, Mohammed Ziaur Sarkar, Md Murshed Hasan Rabbi, Fazle A. Khan, Sirajulislam Ahsan, Chowdhury Rafiqul Birkeland, Nils Kåre Department of Mathematics and Natural Sciences, BRAC University Live Shigella Shigellosis Vaccine This article was published in the Acta Microbiologica et Immunologica Hungarica [© 2017 Akadémiai Kiadó, Budapest] and the definite version is available at : http://doi.org/10.1556/030.64.2017.015 The Journal's website is at: http://akademiai.com/doi/abs/10.1556/030.64.2017.015 Recently, we reported the induction of protective immunity by environmental Escherichia albertii strain DM104 against Shigella dysenteriae in Guinea pig model. In this study, we assessed three different immunization routes, such as intranasal, oral, and intrarectal routes, and revealed differences in immune responses by measuring both the serum IgG and mucosal IgA antibody titers. Protective efficacy of different routes of immunization was also determined by challenging immunized Guinea pigs against live S. dysenteriae. It was found that intranasal immunization showed promising results in terms of antibody response and protective efficacy. All these results reconfirm our previous findings and additionally point out that the intranasal immunization of the environmental E. albertii strain DM104 in Guinea pig model can be a better live vaccine candidate against shigellosis. Published 2018-02-11T05:59:28Z 2018-02-11T05:59:28Z 2017-06 Article Chowdhury, F. M., Rahman, M. Z., Sarkar, M. M. H., Rabbi, F., Khan, S. I., Ahsan, C. R., & Birkeland, N. -. (2017). Protection against shigellosis caused by shigella dysenteriae serotype 4 in guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain. Acta Microbiologica Et Immunologica Hungarica, 64(2), 151-164. 10.1556/030.64.2017.015 12178950 http://hdl.handle.net/10361/9432 http://doi.org/10.1556/030.64.2017.015 en http://akademiai.com/doi/abs/10.1556/030.64.2017.015 © 2017 Akadémiai Kiadó |
| institution |
Brac University |
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Institutional Repository |
| language |
English |
| topic |
Live Shigella Shigellosis Vaccine |
| spellingShingle |
Live Shigella Shigellosis Vaccine Chowdhury, Fatema Moni Rahman, Mohammed Ziaur Sarkar, Md Murshed Hasan Rabbi, Fazle A. Khan, Sirajulislam Ahsan, Chowdhury Rafiqul Birkeland, Nils Kåre Protection against shigellosis caused by shigella dysenteriae serotype 4 in Guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain |
| description |
This article was published in the Acta Microbiologica et Immunologica Hungarica [© 2017 Akadémiai Kiadó, Budapest] and the definite version is available at : http://doi.org/10.1556/030.64.2017.015 The Journal's website is at: http://akademiai.com/doi/abs/10.1556/030.64.2017.015 |
| author2 |
Department of Mathematics and Natural Sciences, BRAC University |
| author_facet |
Department of Mathematics and Natural Sciences, BRAC University Chowdhury, Fatema Moni Rahman, Mohammed Ziaur Sarkar, Md Murshed Hasan Rabbi, Fazle A. Khan, Sirajulislam Ahsan, Chowdhury Rafiqul Birkeland, Nils Kåre |
| format |
Article |
| author |
Chowdhury, Fatema Moni Rahman, Mohammed Ziaur Sarkar, Md Murshed Hasan Rabbi, Fazle A. Khan, Sirajulislam Ahsan, Chowdhury Rafiqul Birkeland, Nils Kåre |
| author_sort |
Chowdhury, Fatema Moni |
| title |
Protection against shigellosis caused by shigella dysenteriae serotype 4 in Guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain |
| title_short |
Protection against shigellosis caused by shigella dysenteriae serotype 4 in Guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain |
| title_full |
Protection against shigellosis caused by shigella dysenteriae serotype 4 in Guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain |
| title_fullStr |
Protection against shigellosis caused by shigella dysenteriae serotype 4 in Guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain |
| title_full_unstemmed |
Protection against shigellosis caused by shigella dysenteriae serotype 4 in Guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain |
| title_sort |
protection against shigellosis caused by shigella dysenteriae serotype 4 in guinea pigs using escherichia albertii dm104 as a live vaccine candidate strain |
| publisher |
© 2017 Akadémiai Kiadó |
| publishDate |
2018 |
| url |
http://hdl.handle.net/10361/9432 http://doi.org/10.1556/030.64.2017.015 |
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