The Generating factors of antimicrobial peptide’s production in human
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2017.
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BRAC University
2018
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| オンライン･アクセス: | http://hdl.handle.net/10361/9397 |
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10361-93972019-09-30T03:19:06Z The Generating factors of antimicrobial peptide’s production in human Mahbub, Jerin Mahzabeen, Sinayat Department of Pharmacy, BRAC University Generating factors Antimicrobial Peptide’s production This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2017. Cataloged from PDF version of project report. Includes bibliographical references (page 40-51). Antimicrobial peptide (AMP) has been recognized as a noble antibiotic against wide range of bacteria now a days. Isolated AMPs from various sources are used to control a number of diseases in humans. To reinforce their expression, some factors can be used to work on specific parts of human body. In this study, we accumulate seven factors which assist production of cathelicidin and defensins family of human AMPs. Vitamin D3 and bile salt prompt up cathelicidin expression in various epithelial cell lines through vitamin D receptor and farnesoid X receptor as respectively. On the other side, beta defensins can be induced by epigallocatechin-3-gallate, isoleucine, sulphoraphane and platelet release growth factor in targeted areas. Lastly, phenylbutyrate works on both cathelicidin and beta defensin 1. Most of them work effectively in dose and time dependent manner. In some cases, the combination therapy of two or three of them have been turned out positively than their individual action which is also highlighted here. In spite of their usefulness, some obstacles are still lagging behind them from implementation which need further investigation. This study clearly indicates that all the elements successfully elevate antimicrobial peptide expression within the body and also improve innate immunity to fight against infections in both primary and critical stages. Jerin Mahbub B. Pharmacy. 2018-02-06T06:15:13Z 2018-02-06T06:15:13Z 2017 2017-07-26 Project report ID 13146032 http://hdl.handle.net/10361/9397 en BRAC University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 51 pages. application/pdf BRAC University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Generating factors Antimicrobial Peptide’s production |
| spellingShingle |
Generating factors Antimicrobial Peptide’s production Mahbub, Jerin The Generating factors of antimicrobial peptide’s production in human |
| description |
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2017. |
| author2 |
Mahzabeen, Sinayat |
| author_facet |
Mahzabeen, Sinayat Mahbub, Jerin |
| format |
Project report |
| author |
Mahbub, Jerin |
| author_sort |
Mahbub, Jerin |
| title |
The Generating factors of antimicrobial peptide’s production in human |
| title_short |
The Generating factors of antimicrobial peptide’s production in human |
| title_full |
The Generating factors of antimicrobial peptide’s production in human |
| title_fullStr |
The Generating factors of antimicrobial peptide’s production in human |
| title_full_unstemmed |
The Generating factors of antimicrobial peptide’s production in human |
| title_sort |
generating factors of antimicrobial peptide’s production in human |
| publisher |
BRAC University |
| publishDate |
2018 |
| url |
http://hdl.handle.net/10361/9397 |
| work_keys_str_mv |
AT mahbubjerin thegeneratingfactorsofantimicrobialpeptidesproductioninhuman AT mahbubjerin generatingfactorsofantimicrobialpeptidesproductioninhuman |
| _version_ |
1814307775112544256 |