Phytochemical and biological investigation of persicaria glabra
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2017.
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BRAC University
2018
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| Sarrera elektronikoa: | http://hdl.handle.net/10361/9293 |
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10361-9293 |
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10361-92932019-09-30T02:59:11Z Phytochemical and biological investigation of persicaria glabra Chakma, Utsha Podder, Ashis Kumar Department of Pharmacy, BRAC University Phytochemical and biological Persicaria glabra Biological investigation This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2017. Cataloged from PDF version of project report. Includes bibliographical references (page 52-54). Present study was performed to establish the scientific basis of the use of Persicaria glabra as one of the curing and therapeutic agents of traditional practices in Bangladesh. The methanolic extract of the leaves was subjected to in vitro biological investigation for antioxidant test (Total phenolic content and DPPH assay), antimicrobial test (Disc diffusion method) and cytotoxicity test (Brine shrimp lethality bioassay). The plant extract showed potent cytotoxic activity nearly equivalent to standard vincristine sulfate compound. The study also confirmed presence of good amount of total phenolic content and free radical scavenging activity by DPPH method. Antimicrobial screening also done by the extract but it showed low antimicrobial activity compared to standard antimicrobial agent (kanamycin). However, more investigation is needed to identify in vitro anticancer activity on human cell line for the justification of its traditional use for squamous cell carcinoma and high cytotoxic activity of the leaf extract. Utsha Chakma B. Pharmacy 2018-01-30T10:18:35Z 2018-01-30T10:18:35Z 2017 2017-07-09 Project report ID 12346001 http://hdl.handle.net/10361/9293 en BRAC University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 54 pages application/pdf BRAC University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Phytochemical and biological Persicaria glabra Biological investigation |
| spellingShingle |
Phytochemical and biological Persicaria glabra Biological investigation Chakma, Utsha Phytochemical and biological investigation of persicaria glabra |
| description |
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2017. |
| author2 |
Podder, Ashis Kumar |
| author_facet |
Podder, Ashis Kumar Chakma, Utsha |
| format |
Project report |
| author |
Chakma, Utsha |
| author_sort |
Chakma, Utsha |
| title |
Phytochemical and biological investigation of persicaria glabra |
| title_short |
Phytochemical and biological investigation of persicaria glabra |
| title_full |
Phytochemical and biological investigation of persicaria glabra |
| title_fullStr |
Phytochemical and biological investigation of persicaria glabra |
| title_full_unstemmed |
Phytochemical and biological investigation of persicaria glabra |
| title_sort |
phytochemical and biological investigation of persicaria glabra |
| publisher |
BRAC University |
| publishDate |
2018 |
| url |
http://hdl.handle.net/10361/9293 |
| work_keys_str_mv |
AT chakmautsha phytochemicalandbiologicalinvestigationofpersicariaglabra |
| _version_ |
1814308875948523520 |