Phytochemical screening and the analysis of antibacterial activity in Chrysanthemum morifolium Ramat

This dissertation is submitted in partial fulfilment of the requirements for the degree of Bachelor of Science in Biotechnology, 2017.

Detalles Bibliográficos
Autor principal: Nowrid, Nazia
Otros Autores: Chowdhury, Jebunnesa
Formato: Tesis
Lenguaje:English
Publicado: BRAC University 2018
Materias:
Acceso en línea:http://hdl.handle.net/10361/9111
id 10361-9111
record_format dspace
spelling 10361-91112019-09-30T04:30:07Z Phytochemical screening and the analysis of antibacterial activity in Chrysanthemum morifolium Ramat Nowrid, Nazia Chowdhury, Jebunnesa Department of Mathematics and Natural Sciences, BRAC University Chrysanthemum morifolium Ramat Anti-bacteria Phytochemical screening This dissertation is submitted in partial fulfilment of the requirements for the degree of Bachelor of Science in Biotechnology, 2017. Cataloged from PDF version of thesis report. Includes bibliographical references (page 46-49). Chrysanthemum morifolium Ramat is a plant of the family Asteraceae and native to Asia and northeastern Europe. It has many pharmacological and therapeutic properties including antimicrobial, antifungal, anti-inflammatory, immunomodulatory humoral and cellular, and mononuclear phagocytic activities; therefore widely and effectively being used in the treatment of many diseases as a herbal medicine. Essentially, medicinal plants are known to have the ability to synthesize a wide range of chemical compounds and secondary metabolites; also the active biological functions and medicinal values of such plants is attributed to the presence of bioactive compounds. In the present study, Chrysanthemum leaves were analyzed for preliminary phytochemical studies to find the presence of phytoconstituents such as alkaloids, flavonoids, steroidal compounds, saponins, tannins, phenols and cardiac glycosides. The crude plant extract from two different extractions (ethanol and methanol) were collected and tested. Comparative analysis of the antimicrobial activity of the extracts was investigated against five bacterial strains namely: Bacillus cereus, Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli and Shigella flexneri. This test was done using agar disc diffusion method and as controls kanamycin, ampicillin, chloramphenicol, ciprofloxacin and cefotoxin were used. The diameter of the clear zone of inhibition surrounding the disc was measured in millimeters. The results showed that the ethanolic extracts of Chrysanthemum morifolium Ramat contained the highest amounts of phytochemicals, while the methanolic extract contained a substantial amount. Antibacterial activity results showed that the highest amount inhibition was formed against B.cereus and then in S.aureus and S.flexneri. It can be concluded from the results that methanolic and ethanolic extracts of Chrysanthemum morifolium Ramat may be considered as an antibacterial agent against B.cereus, S.aureus, S.flexneri and be used to source antibiotic substances. Nazia Nowrid B. Biotechnology 2018-01-21T05:36:42Z 2018-01-21T05:36:42Z 2017 2017-06-19 Thesis ID 13136017 http://hdl.handle.net/10361/9111 en BRAC University dissertations are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 51 pages application/pdf BRAC University
institution Brac University
collection Institutional Repository
language English
topic Chrysanthemum morifolium Ramat
Anti-bacteria
Phytochemical screening
spellingShingle Chrysanthemum morifolium Ramat
Anti-bacteria
Phytochemical screening
Nowrid, Nazia
Phytochemical screening and the analysis of antibacterial activity in Chrysanthemum morifolium Ramat
description This dissertation is submitted in partial fulfilment of the requirements for the degree of Bachelor of Science in Biotechnology, 2017.
author2 Chowdhury, Jebunnesa
author_facet Chowdhury, Jebunnesa
Nowrid, Nazia
format Thesis
author Nowrid, Nazia
author_sort Nowrid, Nazia
title Phytochemical screening and the analysis of antibacterial activity in Chrysanthemum morifolium Ramat
title_short Phytochemical screening and the analysis of antibacterial activity in Chrysanthemum morifolium Ramat
title_full Phytochemical screening and the analysis of antibacterial activity in Chrysanthemum morifolium Ramat
title_fullStr Phytochemical screening and the analysis of antibacterial activity in Chrysanthemum morifolium Ramat
title_full_unstemmed Phytochemical screening and the analysis of antibacterial activity in Chrysanthemum morifolium Ramat
title_sort phytochemical screening and the analysis of antibacterial activity in chrysanthemum morifolium ramat
publisher BRAC University
publishDate 2018
url http://hdl.handle.net/10361/9111
work_keys_str_mv AT nowridnazia phytochemicalscreeningandtheanalysisofantibacterialactivityinchrysanthemummorifoliumramat
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