Phytochemical screening and study of analgesic potential of Pandanus fascicularis different root extract in experimental animal model
This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2016
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BRAC University
2017
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| Accés en línia: | http://hdl.handle.net/10361/7618 |
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10361-76182019-09-30T03:17:15Z Phytochemical screening and study of analgesic potential of Pandanus fascicularis different root extract in experimental animal model Asha, Saima Zaman Ripa, Mrs. Farhana Alam Department of Pharmacy, BRAC University Pandanusfascicularis Chemical Acetic acid This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2016 Cataloged from PDF version of project report. Includes bibliographical references (page 50-52). The aim of this study was to investigate phytochemicalcompoundsand study of analgesic activity ofdifferent root extracts like [ethanol (EAPF), chloroform (CHPF) and ethyl acetate (EAPF)]ofPandanusfascicularis. For analgesic activity we have performed acetic acid induced writhing method and formalin induced pain method. Different extracts were tested for qualitative chemical analysis which reveals the presence of alkaloids, glycosides, carbohydrate and tannin. In our present study we administered our experimented crude extracts at two doses 250 mg/kg and 500 mg/kg to evaluate the analgesic activity in rodents. Both doses of extracts significantly (p<0.01) inhibited writhing response induced by acetic acid and formalin. The experimental extracts have satisfactory analgesic effect compare to control group and represented by number of writhes in acetic acid induced pain method as well as number of licking time in formalin induced licking method. The EAPF extract, at 250 mg/kg dose showed 85.7 % and at 500 mg/kg showed 88.12 % inhibition of writing response compare to reference Indomethacine(58.50%) inhibition was observed. In conclusion we can say that the different root extracts of Pandanusfascicularis contain some active phytochemical constituents which are responsible for the observation of analgesic activity and this amply justify the traditional use of this plant as a pain reliever. Saima Zaman Asha B. Pharmacy 2017-01-19T04:39:43Z 2017-01-19T04:39:43Z 2016 2016-09 Project report ID 11146023 http://hdl.handle.net/10361/7618 en BRAC University project report are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 52 pages application/pdf BRAC University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Pandanusfascicularis Chemical Acetic acid |
| spellingShingle |
Pandanusfascicularis Chemical Acetic acid Asha, Saima Zaman Phytochemical screening and study of analgesic potential of Pandanus fascicularis different root extract in experimental animal model |
| description |
This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2016 |
| author2 |
Ripa, Mrs. Farhana Alam |
| author_facet |
Ripa, Mrs. Farhana Alam Asha, Saima Zaman |
| format |
Project report |
| author |
Asha, Saima Zaman |
| author_sort |
Asha, Saima Zaman |
| title |
Phytochemical screening and study of analgesic potential of Pandanus fascicularis different root extract in experimental animal model |
| title_short |
Phytochemical screening and study of analgesic potential of Pandanus fascicularis different root extract in experimental animal model |
| title_full |
Phytochemical screening and study of analgesic potential of Pandanus fascicularis different root extract in experimental animal model |
| title_fullStr |
Phytochemical screening and study of analgesic potential of Pandanus fascicularis different root extract in experimental animal model |
| title_full_unstemmed |
Phytochemical screening and study of analgesic potential of Pandanus fascicularis different root extract in experimental animal model |
| title_sort |
phytochemical screening and study of analgesic potential of pandanus fascicularis different root extract in experimental animal model |
| publisher |
BRAC University |
| publishDate |
2017 |
| url |
http://hdl.handle.net/10361/7618 |
| work_keys_str_mv |
AT ashasaimazaman phytochemicalscreeningandstudyofanalgesicpotentialofpandanusfascicularisdifferentrootextractinexperimentalanimalmodel |
| _version_ |
1814309757801988096 |