Evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of Bangladesh
This article was published in the International Journal of Mycobacteriology [ © 2014 Elsevier Ltd. ] and the definite version is available at :http://dx.doi.org/10.1016/j.ijmyco.2014.03.003 The Journal's website is at: http://linkinghub.elsevier.com/retrieve/pii/S2212553114000284
| 主要な著者: | , , , , , |
|---|---|
| その他の著者: | |
| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
© 2014 Elsevier Ltd
2016
|
| 主題: | |
| オンライン･アクセス: | http://hdl.handle.net/10361/7188 http://dx.doi.org/10.1016/j.ijmyco.2014.03.003 |
| id |
10361-7188 |
|---|---|
| record_format |
dspace |
| spelling |
10361-71882016-12-11T10:57:58Z Evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of Bangladesh Islam, Mohammad Tariqul Rabbi, Fazle Ferdous, Shameema Parvin, Ummey Shahnaz Hossain, Akram Hossain, Mohammad Sorowar Department of Mathematics and Natural Sciences, BRAC University Bangladesh Immunological tests Pulmonary tuberculosis This article was published in the International Journal of Mycobacteriology [ © 2014 Elsevier Ltd. ] and the definite version is available at :http://dx.doi.org/10.1016/j.ijmyco.2014.03.003 The Journal's website is at: http://linkinghub.elsevier.com/retrieve/pii/S2212553114000284 Objective: Bangladesh is a high tuberculosis burden country. It is always challenging to diagnose active pulmonary tuberculosis (PTB) cases in rural areas where the setting up of conventional microscopic and cultural diagnostic tools is difficult. The objective of the present study is to find a feasible, reliable and easily accessible alternative diagnostic approach for PTB in the rural areas of Bangladesh. Methods: A total of 86 sputum samples were collected from clinically suspected PTB patients of Anantapur village, an underdeveloped remote area of Netrokona district, Bangladesh. Sputum samples were screened by Ziehl-Neelsen (Z-N) and fluorescence staining methods and were categorized as smear-positive active PTB cases (n= 50) and smear-negative controls (n= 36); then the performance of three popular immunological tests were evaluated, including ICT, ELISA and Mantoux tests (MT). Results: The sensitivity of ICT, ELISA, and MT (10. mm induration size) was 68%, 84% and 96%, respectively, and the specificity of these tests was 94.4%, 80.6% and 52.8%, respectively. When the cut-off size of induration in MT was changed from 10 to ≥15. mm, the sensitivity and specificity of MT became 92% and 83.3%, respectively. It was also found that the interpretation of MT was not significantly affected by BCG vaccination when ≥15. mm induration was taken as a cut-off value. Conclusion: Considering the resource-constraints of rural and remote areas, the Mantoux test could be an alternative tool for the diagnosis of active PTB. Published 2016-12-11T10:53:55Z 2016-12-11T10:53:55Z 2014-06 Article Islam, M. T., Rabbi, F., Ferdous, S., Parvin, U. S., Hossain, A., & Hossain, M. S. (2014). Evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of bangladesh. International Journal of Mycobacteriology, 3(2), 88-93. doi:10.1016/j.ijmyco.2014.03.003 22125531 http://hdl.handle.net/10361/7188 http://dx.doi.org/10.1016/j.ijmyco.2014.03.003 en http://linkinghub.elsevier.com/retrieve/pii/S2212553114000284 © 2014 Elsevier Ltd |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Bangladesh Immunological tests Pulmonary tuberculosis |
| spellingShingle |
Bangladesh Immunological tests Pulmonary tuberculosis Islam, Mohammad Tariqul Rabbi, Fazle Ferdous, Shameema Parvin, Ummey Shahnaz Hossain, Akram Hossain, Mohammad Sorowar Evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of Bangladesh |
| description |
This article was published in the International Journal of Mycobacteriology [ © 2014 Elsevier Ltd. ] and the definite version is available at :http://dx.doi.org/10.1016/j.ijmyco.2014.03.003 The Journal's website is at: http://linkinghub.elsevier.com/retrieve/pii/S2212553114000284 |
| author2 |
Department of Mathematics and Natural Sciences, BRAC University |
| author_facet |
Department of Mathematics and Natural Sciences, BRAC University Islam, Mohammad Tariqul Rabbi, Fazle Ferdous, Shameema Parvin, Ummey Shahnaz Hossain, Akram Hossain, Mohammad Sorowar |
| format |
Article |
| author |
Islam, Mohammad Tariqul Rabbi, Fazle Ferdous, Shameema Parvin, Ummey Shahnaz Hossain, Akram Hossain, Mohammad Sorowar |
| author_sort |
Islam, Mohammad Tariqul |
| title |
Evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of Bangladesh |
| title_short |
Evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of Bangladesh |
| title_full |
Evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of Bangladesh |
| title_fullStr |
Evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of Bangladesh |
| title_full_unstemmed |
Evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of Bangladesh |
| title_sort |
evaluation of three immunological tests for the diagnosis of pulmonary tuberculosis in a rural endemic area of bangladesh |
| publisher |
© 2014 Elsevier Ltd |
| publishDate |
2016 |
| url |
http://hdl.handle.net/10361/7188 http://dx.doi.org/10.1016/j.ijmyco.2014.03.003 |
| work_keys_str_mv |
AT islammohammadtariqul evaluationofthreeimmunologicaltestsforthediagnosisofpulmonarytuberculosisinaruralendemicareaofbangladesh AT rabbifazle evaluationofthreeimmunologicaltestsforthediagnosisofpulmonarytuberculosisinaruralendemicareaofbangladesh AT ferdousshameema evaluationofthreeimmunologicaltestsforthediagnosisofpulmonarytuberculosisinaruralendemicareaofbangladesh AT parvinummeyshahnaz evaluationofthreeimmunologicaltestsforthediagnosisofpulmonarytuberculosisinaruralendemicareaofbangladesh AT hossainakram evaluationofthreeimmunologicaltestsforthediagnosisofpulmonarytuberculosisinaruralendemicareaofbangladesh AT hossainmohammadsorowar evaluationofthreeimmunologicaltestsforthediagnosisofpulmonarytuberculosisinaruralendemicareaofbangladesh |
| _version_ |
1814307531253612544 |