In vivo measurement of the surface energy of human fingernail plates

This article was published in the International Journal of Cosmetic Science [© 2012 International Journal of Cosmetic Science] and the definite version is available at: http://discovery.ucl.ac.uk/1366902/1/nail_surface_energy_for_SOPwebsite.pdf

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Príomhchruthaitheoirí: Zara, Sheikh, Murdan, Sudaxshina, Poojary, Chitranjan, Patel, Dilan R, Fernandes, João, Angarju
Rannpháirtithe: Department of Pharmacy, BRAC University
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: © 2012 International Journal of Cosmetic Science 2016
Ábhair:
Rochtain ar líne:http://hdl.handle.net/10361/7090
http://doi.org/10.1111/j.1468-2494.2012.00711.x
id 10361-7090
record_format dspace
spelling 10361-70902016-12-06T03:21:32Z In vivo measurement of the surface energy of human fingernail plates Zara, Sheikh, Murdan, Sudaxshina Poojary, Chitranjan Patel, Dilan R Fernandes, João Angarju Department of Pharmacy, BRAC University Nail Surface energy Hydration Abrasion Hoof This article was published in the International Journal of Cosmetic Science [© 2012 International Journal of Cosmetic Science] and the definite version is available at: http://discovery.ucl.ac.uk/1366902/1/nail_surface_energy_for_SOPwebsite.pdf The surface energy of the human nail plate is expected to influence the adhesion of microorganisms (and subsequent colonization and infections) as well as that of medicines (and subsequent drug permeation) and of cosmetics. The aim of the study was therefore to measure the surface energy of nail plates in vivo. The surface energy of healthy human fingernails (untreated, hydrated and abraded) and of hoof membranes (often used as a model for the nail plate) was estimated from contact angle measurements of liquids (water, formamide, diiodomethane and glycerol) on the nail plate and subsequent computation using the Lifshitz–van der Waals/acid–base (LW-AB) approach. The surface energy of untreated fingernail plates was found to be 34 mJ m−2. Most of this total energy was from the apolar Lifshitz–van der Waals component. When the polar component of the surface energy was analysed, the electron donor component was considerably larger than the electron acceptor one. Hydrating the nail plate had no significant influence on the surface energy. In contrast, abrasion caused a small, but statistically significant increase in the apolar surface energy component. The surface energy of bovine hoof membrane was similar to that of the fingernail plate. We conclude that the human fingernail plate is a low-energy surface and that bovine hoof membranes may be used as a substitute for the nail plate in certain experiments. Published 2016-12-03T20:49:30Z 2016-12-03T20:49:30Z 2012-03 Article S udaxshina , M., Poojary, C., R Patel, ilan, Fernandes, oão, Haman, A., Saundh, P. S., & Sheikh, Z. (2012). In vivo measurement of the surface energy of human fingernail plates . International Journal of Cosmetic Science, 34, (3) 257–262 . http://hdl.handle.net/10361/7090 http://doi.org/10.1111/j.1468-2494.2012.00711.x en http://discovery.ucl.ac.uk/1366902/1/nail_surface_energy_for_SOPwebsite.pdf © 2012 International Journal of Cosmetic Science
institution Brac University
collection Institutional Repository
language English
topic Nail
Surface energy
Hydration
Abrasion
Hoof
spellingShingle Nail
Surface energy
Hydration
Abrasion
Hoof
Zara, Sheikh,
Murdan, Sudaxshina
Poojary, Chitranjan
Patel, Dilan R
Fernandes, João
Angarju
In vivo measurement of the surface energy of human fingernail plates
description This article was published in the International Journal of Cosmetic Science [© 2012 International Journal of Cosmetic Science] and the definite version is available at: http://discovery.ucl.ac.uk/1366902/1/nail_surface_energy_for_SOPwebsite.pdf
author2 Department of Pharmacy, BRAC University
author_facet Department of Pharmacy, BRAC University
Zara, Sheikh,
Murdan, Sudaxshina
Poojary, Chitranjan
Patel, Dilan R
Fernandes, João
Angarju
format Article
author Zara, Sheikh,
Murdan, Sudaxshina
Poojary, Chitranjan
Patel, Dilan R
Fernandes, João
Angarju
author_sort Zara, Sheikh,
title In vivo measurement of the surface energy of human fingernail plates
title_short In vivo measurement of the surface energy of human fingernail plates
title_full In vivo measurement of the surface energy of human fingernail plates
title_fullStr In vivo measurement of the surface energy of human fingernail plates
title_full_unstemmed In vivo measurement of the surface energy of human fingernail plates
title_sort in vivo measurement of the surface energy of human fingernail plates
publisher © 2012 International Journal of Cosmetic Science
publishDate 2016
url http://hdl.handle.net/10361/7090
http://doi.org/10.1111/j.1468-2494.2012.00711.x
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AT poojarychitranjan invivomeasurementofthesurfaceenergyofhumanfingernailplates
AT pateldilanr invivomeasurementofthesurfaceenergyofhumanfingernailplates
AT fernandesjoao invivomeasurementofthesurfaceenergyofhumanfingernailplates
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