Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium

書目詳細資料
Main Authors:	Dash, Pritesh Ranjan, Sheikh, Zara
其他作者:	Department of Pharmacy, BRAC University
格式:	Article
語言:	English
出版:	© 2015 Journal of Pharmacognosy and Phytochemistry 2016
主題:	Hedychium coronarium Cytotoxicity Brine shrimp Artemia salina
在線閱讀:	http://hdl.handle.net/10361/7086

id	10361-7086
record_format	dspace
spelling	10361-70862016-12-06T04:49:00Z Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium Dash, Pritesh Ranjan Sheikh, Zara Department of Pharmacy, BRAC University Hedychium coronarium Cytotoxicity Brine shrimp Artemia salina This article was published in the Journal of Pharmacognosy and Phytochemistry [©2015 Journal of Pharmacognosy and Phytochemistry] The definite version is available at: https://goo.gl/aChrRS The methanolic extract of the rhizome of Hedychium coronarium (Family- Zingiberaceae) was screened for the presence of various phytochemicals by standard procedures and the cytotoxic activity was evaluated by brine shrimp lethality bioassay. The present study indicates that the rhizome contain carbohydrates, flavonoids, saponins, steroids and alkaloids. In brine shrimp lethality bioassay, the extract showed potent cytotoxic action. The degree of lethality was found to be directly proportional to the concentration of the extract ranging from the lowest concentration (1.25 μg/ml) to the highest concentration (320 μg/ml). The LC50 value of the methanolic rhizome extract was 0.39 μg/ml, whereas the LC50 of the reference anticancer drug vincristine sulphate was 0.52 μg/ml. Published 2016-12-03T18:13:56Z 2016-12-03T18:13:56Z 2015 Article Dash P.R, Sheikh Z (2015). Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium. Journal of Pharmacognosy and Phytochemistry, 4(1): 136-139. 2278-4136 http://hdl.handle.net/10361/7086 en https://goo.gl/aChrRS © 2015 Journal of Pharmacognosy and Phytochemistry
institution	Brac University
collection	Institutional Repository
language	English
topic	Hedychium coronarium Cytotoxicity Brine shrimp Artemia salina
spellingShingle	Hedychium coronarium Cytotoxicity Brine shrimp Artemia salina Dash, Pritesh Ranjan Sheikh, Zara Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium
description	This article was published in the Journal of Pharmacognosy and Phytochemistry [©2015 Journal of Pharmacognosy and Phytochemistry] The definite version is available at: https://goo.gl/aChrRS
author2	Department of Pharmacy, BRAC University
author_facet	Department of Pharmacy, BRAC University Dash, Pritesh Ranjan Sheikh, Zara
format	Article
author	Dash, Pritesh Ranjan Sheikh, Zara
author_sort	Dash, Pritesh Ranjan
title	Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium
title_short	Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium
title_full	Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium
title_fullStr	Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium
title_full_unstemmed	Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium
title_sort	preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of hedychium coronarium
publisher	© 2015 Journal of Pharmacognosy and Phytochemistry
publishDate	2016
url	http://hdl.handle.net/10361/7086
work_keys_str_mv	AT dashpriteshranjan preliminarystudiesonphytochemicalsandcytotoxicactivityofmethanolicrhizomeextractofhedychiumcoronarium AT sheikhzara preliminarystudiesonphytochemicalsandcytotoxicactivityofmethanolicrhizomeextractofhedychiumcoronarium
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Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium

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