Characterization of phytoconstituents and potential bioactivity of Annona reticulata L. leaf extract
This article was published in the Journal of Pharmacognosy and Phytochemistry [©2016 Journal of Pharmacognosy and Phytochemistry]
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| 言語: | English |
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© 2016 Journal of Pharmacognosy and Phytochemistry
2016
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| オンライン･アクセス: | http://hdl.handle.net/10361/7085 |
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10361-70852016-12-03T18:04:26Z Characterization of phytoconstituents and potential bioactivity of Annona reticulata L. leaf extract Shahriar, Mohammad Khair, Nishat Zareen Sheikh, Zara Chowdhury, Sayeeda Fahmee Kamruzzaman, Md. Bakhtiar, Md. Shawkatul Islam Chisty, Sharmin Jahan Department of Pharmacy, BRAC University Annona reticulate Leaf extract Phytoconstituents Membrane stabilizing Thrombolytic activity This article was published in the Journal of Pharmacognosy and Phytochemistry [©2016 Journal of Pharmacognosy and Phytochemistry] Annona reticulata (Annonaceae) is known as atafol in Bangla and custard apple in English is an important medicinal plant. It has been used traditionally in diarrhea, dysentery, cold, as abortifacient, insecticidal drug etc. In this present study, the leaf extracts of Annona reticulata were subjected to evaluation of the thrombolytic activity was assessed by using human erythrocyte and the results were compared with standard streptokinase (SK). The chloroform extract showed 36.82% clot lysis as compared to 93.79% clot lysis produced by standard streptokinase. The leaf extracts of Annona reticulata were subjected to evaluation of the membrane stabilizing activity by using human erythrocyte and the results were compared with standard anti-inflammatory drug, acetyl salicylic acid (ASA). In vitro membrane stabilizing activity for hypotonic solution induced haemolysis, the chloroform extract inhibited 75.15% haemolysis of RBCs as compared to 72.99% produced by acetyl salicylic acid (ASA) and during heat induced condition different organic soluble materials of Annona reticulata demonstrated methanol, ethanol and chloroform extract showed 68.81%, 72.06% and 78.17% inhibition of RBC hemolysis respectively whereas standard acetylsalicylic acid showed 70.87% inhibition of RBC haemolysis. Published 2016-12-03T16:20:10Z 2016-12-03T16:20:10Z 2016 Article 1. Shahriar M, Khair N.Z, Sheikh Z, Chowdhury S.F et al (2016). Characterization of phytoconstituents and potential bioactivity of Annona reticulata L. leaf extract. Journal of Pharmacognosy and Phytochemistry, 5(1): 42-45 2278-4136 http://hdl.handle.net/10361/7085 en © 2016 Journal of Pharmacognosy and Phytochemistry |
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Brac University |
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Institutional Repository |
| language |
English |
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Annona reticulate Leaf extract Phytoconstituents Membrane stabilizing Thrombolytic activity |
| spellingShingle |
Annona reticulate Leaf extract Phytoconstituents Membrane stabilizing Thrombolytic activity Shahriar, Mohammad Khair, Nishat Zareen Sheikh, Zara Chowdhury, Sayeeda Fahmee Kamruzzaman, Md. Bakhtiar, Md. Shawkatul Islam Chisty, Sharmin Jahan Characterization of phytoconstituents and potential bioactivity of Annona reticulata L. leaf extract |
| description |
This article was published in the Journal of Pharmacognosy and Phytochemistry [©2016 Journal of Pharmacognosy and Phytochemistry] |
| author2 |
Department of Pharmacy, BRAC University |
| author_facet |
Department of Pharmacy, BRAC University Shahriar, Mohammad Khair, Nishat Zareen Sheikh, Zara Chowdhury, Sayeeda Fahmee Kamruzzaman, Md. Bakhtiar, Md. Shawkatul Islam Chisty, Sharmin Jahan |
| format |
Article |
| author |
Shahriar, Mohammad Khair, Nishat Zareen Sheikh, Zara Chowdhury, Sayeeda Fahmee Kamruzzaman, Md. Bakhtiar, Md. Shawkatul Islam Chisty, Sharmin Jahan |
| author_sort |
Shahriar, Mohammad |
| title |
Characterization of phytoconstituents and potential bioactivity of Annona reticulata L. leaf extract |
| title_short |
Characterization of phytoconstituents and potential bioactivity of Annona reticulata L. leaf extract |
| title_full |
Characterization of phytoconstituents and potential bioactivity of Annona reticulata L. leaf extract |
| title_fullStr |
Characterization of phytoconstituents and potential bioactivity of Annona reticulata L. leaf extract |
| title_full_unstemmed |
Characterization of phytoconstituents and potential bioactivity of Annona reticulata L. leaf extract |
| title_sort |
characterization of phytoconstituents and potential bioactivity of annona reticulata l. leaf extract |
| publisher |
© 2016 Journal of Pharmacognosy and Phytochemistry |
| publishDate |
2016 |
| url |
http://hdl.handle.net/10361/7085 |
| work_keys_str_mv |
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