Phytochemical analysis, cytotoxic and in vitro antioxidant activity of erythrina variegate bark
This article was published in the European Journal of Medicinal Plants [©2015 European Journal of Medicinal Plants] The Article's website is at: http://www.journalrepository.org/media/journals/EJMP_13/2015/Nov/Shahriar1132015EJMP18866.pdf
| Główni autorzy: | , , , , , , , , , |
|---|---|
| Kolejni autorzy: | |
| Format: | Artykuł |
| Język: | English |
| Wydane: |
© 2015 European Journal of Medicinal Plants
2016
|
| Hasła przedmiotowe: | |
| Dostęp online: | http://hdl.handle.net/10361/7083 |
| id |
10361-7083 |
|---|---|
| record_format |
dspace |
| spelling |
10361-70832016-12-06T04:51:06Z Phytochemical analysis, cytotoxic and in vitro antioxidant activity of erythrina variegate bark Shahriar, Mohammad Khair, Nishat Zareen Sheikh, Zara Chowdhury, Sayeeda Fahmee Kamruzzaman, Md. Bakhtiar, Md. Shawkatul Islam Chisty, Sharmin Jahan Narjish, Syeda Najah Akhter, Rumana Akter, Nahia Department of Pharmacy, BRAC University Erythrina variegate Phytochemicals Antioxidant capacities Cytotoxicity This article was published in the European Journal of Medicinal Plants [©2015 European Journal of Medicinal Plants] The Article's website is at: http://www.journalrepository.org/media/journals/EJMP_13/2015/Nov/Shahriar1132015EJMP18866.pdf Aim:The objective of the present study was to investigate the phytochemical analysis, cytotoxic and antioxidant activities of the bark extracts of Erythrina variegate.Place and Duration of Study: The plant, E. variegate was collected from Botanical Garden, Mirpur, Dhaka and also from Curzon Hall, University of Dhaka, Bangladesh in June 2014 and then the sample was identified by the National Herbarium of Bangladesh, Mirpur, Dhaka (DACB; Accession Number- 36148). Methodology: Preliminary phytochemical screening was done for determining the nature of phytoconstituents. Brine shrimp lethality bioassay technique was done to study the cytotoxic properties. Aluminum chloride colorimetric method was applied for the determination of flavonoids and the total antioxidant ability was assessed by the phospho-molybdenum method. Results: Primary phytochemical analysis confirmed the presence of alkaloid, carbohydrate, glycosides and flavonoids. The extracts showed some toxicity to A. salina with LC50 values ranging from 1.41 to 3.66 μ g/ml which was compared with standard vincristine sulphate (VS, LC50 value 0.92 μg/ml). n-Hexane extract of E. variegate was found to contain highest amount of flavonoids (3.77±1.97 mg/gm; quercetin equivalent) and ethanol extract of E. variegate was found to have highest antioxidant acitivity (2.03±0.09 mg/gm ascorbic acid equivalent). Conclusion: It can be concluded that the plant extracts of E. variegate possess several antioxidant activities which justifies its use as folk medicine. Published 2016-12-03T15:31:09Z 2016-12-03T15:31:09Z 2015-11 Article 1. Shahriar M, Khair N.Z, Sheikh Z, Chowdhury S.F et al (2016). Phytochemical Analysis, Cytotoxic and In vitro Antioxidant Activity of Erythrina variegate Bark. European Journal of Medicinal Plants, 11(3): 1-5 2231-0894 http://hdl.handle.net/10361/7083 en http://www.journalrepository.org/media/journals/EJMP_13/2015/Nov/Shahriar1132015EJMP18866.pdf http://www.journalrepository.org/media/journals/EJMP_13/2015/Nov/Shahriar1132015EJMP18866.pdf © 2015 European Journal of Medicinal Plants |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Erythrina variegate Phytochemicals Antioxidant capacities Cytotoxicity |
| spellingShingle |
Erythrina variegate Phytochemicals Antioxidant capacities Cytotoxicity Shahriar, Mohammad Khair, Nishat Zareen Sheikh, Zara Chowdhury, Sayeeda Fahmee Kamruzzaman, Md. Bakhtiar, Md. Shawkatul Islam Chisty, Sharmin Jahan Narjish, Syeda Najah Akhter, Rumana Akter, Nahia Phytochemical analysis, cytotoxic and in vitro antioxidant activity of erythrina variegate bark |
| description |
This article was published in the European Journal of Medicinal Plants [©2015 European Journal of Medicinal Plants] The Article's website is at: http://www.journalrepository.org/media/journals/EJMP_13/2015/Nov/Shahriar1132015EJMP18866.pdf |
| author2 |
Department of Pharmacy, BRAC University |
| author_facet |
Department of Pharmacy, BRAC University Shahriar, Mohammad Khair, Nishat Zareen Sheikh, Zara Chowdhury, Sayeeda Fahmee Kamruzzaman, Md. Bakhtiar, Md. Shawkatul Islam Chisty, Sharmin Jahan Narjish, Syeda Najah Akhter, Rumana Akter, Nahia |
| format |
Article |
| author |
Shahriar, Mohammad Khair, Nishat Zareen Sheikh, Zara Chowdhury, Sayeeda Fahmee Kamruzzaman, Md. Bakhtiar, Md. Shawkatul Islam Chisty, Sharmin Jahan Narjish, Syeda Najah Akhter, Rumana Akter, Nahia |
| author_sort |
Shahriar, Mohammad |
| title |
Phytochemical analysis, cytotoxic and in vitro antioxidant activity of erythrina variegate bark |
| title_short |
Phytochemical analysis, cytotoxic and in vitro antioxidant activity of erythrina variegate bark |
| title_full |
Phytochemical analysis, cytotoxic and in vitro antioxidant activity of erythrina variegate bark |
| title_fullStr |
Phytochemical analysis, cytotoxic and in vitro antioxidant activity of erythrina variegate bark |
| title_full_unstemmed |
Phytochemical analysis, cytotoxic and in vitro antioxidant activity of erythrina variegate bark |
| title_sort |
phytochemical analysis, cytotoxic and in vitro antioxidant activity of erythrina variegate bark |
| publisher |
© 2015 European Journal of Medicinal Plants |
| publishDate |
2016 |
| url |
http://hdl.handle.net/10361/7083 |
| work_keys_str_mv |
AT shahriarmohammad phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark AT khairnishatzareen phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark AT sheikhzara phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark AT chowdhurysayeedafahmee phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark AT kamruzzamanmd phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark AT bakhtiarmdshawkatulislam phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark AT chistysharminjahan phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark AT narjishsyedanajah phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark AT akhterrumana phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark AT akternahia phytochemicalanalysiscytotoxicandinvitroantioxidantactivityoferythrinavariegatebark |
| _version_ |
1814309757059596288 |