Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone

This article was published in Asian Pacific Journal of Tropical Biomedicine [© 2012 Asian Pacific Tropical Biomedical Magazine] and the definite version is available at : http://www.apjtb.com/zz/2012s2/103.pdf The article website is at: http://www.journals.elsevier.com/asian-pacific-journal-of-tropi...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Zahan, Ronok, Ali, Shaikh M Mohsin, Jesmin, Mele, Azad, M Abul Kalam, Islam, M Khairul
Andre forfattere:	Department of Pharmacy, BRAC University
Format:	Article
Sprog:	English
Udgivet:	© 2012 Asian Pacific Tropical Biomedical Magazine. 2016
Fag:	Acetophenone semicarbazone Analgesic activity Anti-inflammatory activity Benzophenone semicarbazone Schiff base
Online adgang:	http://hdl.handle.net/10361/7057

id	10361-7057
record_format	dspace
spelling	10361-70572016-12-01T09:58:09Z Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone Zahan, Ronok Ali, Shaikh M Mohsin Jesmin, Mele Azad, M Abul Kalam Islam, M Khairul Department of Pharmacy, BRAC University Acetophenone semicarbazone Analgesic activity Anti-inflammatory activity Benzophenone semicarbazone Schiff base This article was published in Asian Pacific Journal of Tropical Biomedicine [© 2012 Asian Pacific Tropical Biomedical Magazine] and the definite version is available at : http://www.apjtb.com/zz/2012s2/103.pdf The article website is at: http://www.journals.elsevier.com/asian-pacific-journal-of-tropical-biomedicine/ To study anti-inflammatory and analgesic activities in swiss albino mice, two schiff bases namely acetophenone semicarbazone (ASC) and benzophenone semicarbazone (BSC) were synthesized and characterized. Methods: Two doses of the test compounds 25 and 50 mg/kg (p.o) for each were selected throughout the research work. The anti-inflammatory activity of the test compounds was determined by 'carragenan induced mice paw edema inhibition' method. The analgesic activity was determined by both, 'acetic acid induced writhing' and 'tail immersion' methods. All such data were compared with standard drugs at the dose of 10 mg/kg (p.o.). Results: Both ASC and BSC have showed positive effects as anti-inflammatory and analgesic agents. Anti-inflammatory and analgesic activities of the test compounds at 50 mg/kg (p.o.) were quite comparable to those of standard drugs at 10 mg/kg (p.o.). Conclusion: Both ASC and BSC can be considered as potent anti-inflammatory and analgesic agents. Published 2016-12-01T09:04:46Z 2016-12-01T09:04:46Z 2012-02 Article Ali, S. M. M., Jesmin, M., Azad, M. A. K., Islam, M. K., & Zahan, R. (2012). Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone. Asian Pacific Journal of Tropical Biomedicine, 2(2 SUPPL.), S1036-S1039. doi:10.1016/S2221-1691(12)60357-8 22211691 http://hdl.handle.net/10361/7057 10.1016/S2221-1691(12)60357-8 en http://www.apjtb.com/zz/2012s2/103.pdf © 2012 Asian Pacific Tropical Biomedical Magazine.
institution	Brac University
collection	Institutional Repository
language	English
topic	Acetophenone semicarbazone Analgesic activity Anti-inflammatory activity Benzophenone semicarbazone Schiff base
spellingShingle	Acetophenone semicarbazone Analgesic activity Anti-inflammatory activity Benzophenone semicarbazone Schiff base Zahan, Ronok Ali, Shaikh M Mohsin Jesmin, Mele Azad, M Abul Kalam Islam, M Khairul Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone
description	This article was published in Asian Pacific Journal of Tropical Biomedicine [© 2012 Asian Pacific Tropical Biomedical Magazine] and the definite version is available at : http://www.apjtb.com/zz/2012s2/103.pdf The article website is at: http://www.journals.elsevier.com/asian-pacific-journal-of-tropical-biomedicine/
author2	Department of Pharmacy, BRAC University
author_facet	Department of Pharmacy, BRAC University Zahan, Ronok Ali, Shaikh M Mohsin Jesmin, Mele Azad, M Abul Kalam Islam, M Khairul
format	Article
author	Zahan, Ronok Ali, Shaikh M Mohsin Jesmin, Mele Azad, M Abul Kalam Islam, M Khairul
author_sort	Zahan, Ronok
title	Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone
title_short	Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone
title_full	Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone
title_fullStr	Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone
title_full_unstemmed	Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone
title_sort	anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone
publisher	© 2012 Asian Pacific Tropical Biomedical Magazine.
publishDate	2016
url	http://hdl.handle.net/10361/7057
work_keys_str_mv	AT zahanronok antiinflammatoryandanalgesicactivitiesofacetophenonesemicarbazoneandbenzophenonesemicarbazone AT alishaikhmmohsin antiinflammatoryandanalgesicactivitiesofacetophenonesemicarbazoneandbenzophenonesemicarbazone AT jesminmele antiinflammatoryandanalgesicactivitiesofacetophenonesemicarbazoneandbenzophenonesemicarbazone AT azadmabulkalam antiinflammatoryandanalgesicactivitiesofacetophenonesemicarbazoneandbenzophenonesemicarbazone AT islammkhairul antiinflammatoryandanalgesicactivitiesofacetophenonesemicarbazoneandbenzophenonesemicarbazone
_version_	1814308595372654592

Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone

Lignende værker