Anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of Nephelium longan fruits in rats
This article was published in Iranian Journal of Pharmacology and Therapeutics [© 2013 Iranian Journal of Pharmacology and Therapeutics] and the definite version is available at: http://ijpt.iums.ac.ir/index.php/ijpt/article/view/1141/515 The article website is at: http://ijpt.iums.ac.ir/index.php/i...
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© 2013 Iranian Journal of Pharmacology and Therapeutics
2016
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| অনলাইন ব্যবহার করুন: | http://hdl.handle.net/10361/6976 |
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10361-69762016-11-24T21:00:07Z Anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of Nephelium longan fruits in rats Ripa, Farhana Alam Habib, Afroza Department of Pharmacy, BRAC University Anti-diarrhoeal activity Anti-inflammatory Nephelium longan This article was published in Iranian Journal of Pharmacology and Therapeutics [© 2013 Iranian Journal of Pharmacology and Therapeutics] and the definite version is available at: http://ijpt.iums.ac.ir/index.php/ijpt/article/view/1141/515 The article website is at: http://ijpt.iums.ac.ir/index.php/ijpt Herbal medicines are playing a vital role in the remedy of numerous diseases. Preliminary phytochemical screening of the methanolic extracts of seeds (MNLS) and peel (MNLP) of Nephelium longan revealed the presence of alkaloids, tannins and flavonoids. For antidairrheal screening, we have followed Castoroil- induced method whereas to check anti-inflammatory property, we used carrageenan-iduced rat paw edema in Long-Evan rats. Two doses (250 and 500 mg/Kg) of the extracts and one dose of indomethacin as reference was used. Both extracts significantly (p < 0.05) reduced the formation of oedema induced by carrageenan in a dose-depending manner. MNLP and MNLS also exhibited anti-diarrheal action in dosedepending manner and all the results were found to be significant (p < 0.05) in comparison to loperamide. The outcomes indicate the potent anti-inflammatory and anti-diarrhoeal effects of N longan extracts on living models which are comparable with those of standard drugs such as indomethacin and loperamide respectively and support their conventional uses as medicine. Published 2016-11-24T15:23:07Z 2016-11-24T15:23:07Z 2013 Article Ripa, F. A., & Habib, A. (2013). Anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of nephelium longan fruits in rats. Iranian Journal of Pharmacology and Therapeutics, 12(2), 58-61. 17352657 http://hdl.handle.net/10361/6976 en http://ijpt.iums.ac.ir/index.php/ijpt/article/view/1141/515 application/msword © 2013 Iranian Journal of Pharmacology and Therapeutics |
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Brac University |
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Institutional Repository |
| language |
English |
| topic |
Anti-diarrhoeal activity Anti-inflammatory Nephelium longan |
| spellingShingle |
Anti-diarrhoeal activity Anti-inflammatory Nephelium longan Ripa, Farhana Alam Habib, Afroza Anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of Nephelium longan fruits in rats |
| description |
This article was published in Iranian Journal of Pharmacology and Therapeutics [© 2013 Iranian Journal of Pharmacology and Therapeutics] and the definite version is available at: http://ijpt.iums.ac.ir/index.php/ijpt/article/view/1141/515 The article website is at: http://ijpt.iums.ac.ir/index.php/ijpt |
| author2 |
Department of Pharmacy, BRAC University |
| author_facet |
Department of Pharmacy, BRAC University Ripa, Farhana Alam Habib, Afroza |
| format |
Article |
| author |
Ripa, Farhana Alam Habib, Afroza |
| author_sort |
Ripa, Farhana Alam |
| title |
Anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of Nephelium longan fruits in rats |
| title_short |
Anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of Nephelium longan fruits in rats |
| title_full |
Anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of Nephelium longan fruits in rats |
| title_fullStr |
Anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of Nephelium longan fruits in rats |
| title_full_unstemmed |
Anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of Nephelium longan fruits in rats |
| title_sort |
anti-inflammatory and anti-diarrheal effects of methanolic extracts of seeds and peel of nephelium longan fruits in rats |
| publisher |
© 2013 Iranian Journal of Pharmacology and Therapeutics |
| publishDate |
2016 |
| url |
http://hdl.handle.net/10361/6976 |
| work_keys_str_mv |
AT ripafarhanaalam antiinflammatoryandantidiarrhealeffectsofmethanolicextractsofseedsandpeelofnepheliumlonganfruitsinrats AT habibafroza antiinflammatoryandantidiarrhealeffectsofmethanolicextractsofseedsandpeelofnepheliumlonganfruitsinrats |
| _version_ |
1814307529885220864 |