Qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements
This article was published in the Asian Journal of Pharmaceutical & Clinical Research [© 2014 Asian Journal of Pharmaceutical & Clinical Research] and the definite version is available at: http://innovareacademics.in/journals/index.php/ajpcr/article/view/987/760
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© 2014 Asian Journal of Pharmaceutical and Clinical Research
2016
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| Acceso en liña: | http://hdl.handle.net/10361/6819 |
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10361-68192016-12-04T08:50:02Z Qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements Podder, Ashis Kumar Chakrobarty, Jayanta Kishor Faroque, A. B. M. Department of Pharmacy, BRAC University HPLC and validation IR Sildenafil Traditional medicines This article was published in the Asian Journal of Pharmaceutical & Clinical Research [© 2014 Asian Journal of Pharmaceutical & Clinical Research] and the definite version is available at: http://innovareacademics.in/journals/index.php/ajpcr/article/view/987/760 Objective: Use of traditional medicines as aphrodisiac and sex stimulant products is a common phenomenon worldwide as well as in our country. In addition to that, in the name of dietary supplements, a number of urban people are using these items as the source of their sex potential. These products ought to be responsible for raising several sexual violence and perversion in the society. That's why these products need to be tested whether they contain only natural ingredients or any other allopathic active pharmaceutical ingredients (APIs). Methods:High performance liquid chromatography was carried out using a C18 column with a mobile phase composed of (diluted sulfuric acid:acetonitrile=60:40) and detected at the wavelength of 290nm. Presence of sildenafil in the identified products was further confirmed by infrared (IR) spectroscopy. Results:In the study, found that 5 out of 25 traditional medicines and 7 out of 10 dietary supplements contain sildenafil. In addition to that 4 out of total 35 samples were found to contain sildenafil that was exceeding the highest dose (100mg per dosage unit) recommended by the manufacturer (Pfizer,UK) of the brand product ViagraTM. Notably noneof the samples were labelled to contain sildenafil. Conclusion:About 35% of the market samples were adulterated with sildenafil. The developed method is simple, precise, specific, accurate, robust, and cost-effective. Hence it can be used for qualitative and quantitative analysis of sildenafil in falsified market products. Published 2016-11-14T10:04:44Z 2016-11-14T10:04:44Z 2014 Article Podder, A. K., Chakrobarty, J. K., & Faroque, A. B. M. (2014). Qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements. Asian Journal of Pharmaceutical and Clinical Research, 7(SUPPL. 2), 25-30 09742441 http://hdl.handle.net/10361/6819 © 2014 Asian Journal of Pharmaceutical and Clinical Research |
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Brac University |
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Institutional Repository |
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HPLC and validation IR Sildenafil Traditional medicines |
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HPLC and validation IR Sildenafil Traditional medicines Podder, Ashis Kumar Chakrobarty, Jayanta Kishor Faroque, A. B. M. Qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements |
| description |
This article was published in the Asian Journal of Pharmaceutical & Clinical Research [© 2014 Asian Journal of Pharmaceutical & Clinical Research] and the definite version is available at: http://innovareacademics.in/journals/index.php/ajpcr/article/view/987/760 |
| author2 |
Department of Pharmacy, BRAC University |
| author_facet |
Department of Pharmacy, BRAC University Podder, Ashis Kumar Chakrobarty, Jayanta Kishor Faroque, A. B. M. |
| format |
Article |
| author |
Podder, Ashis Kumar Chakrobarty, Jayanta Kishor Faroque, A. B. M. |
| author_sort |
Podder, Ashis Kumar |
| title |
Qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements |
| title_short |
Qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements |
| title_full |
Qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements |
| title_fullStr |
Qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements |
| title_full_unstemmed |
Qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements |
| title_sort |
qualitative and quantitative analysis of sildenafil in traditional medicines and dietary supplements |
| publisher |
© 2014 Asian Journal of Pharmaceutical and Clinical Research |
| publishDate |
2016 |
| url |
http://hdl.handle.net/10361/6819 |
| work_keys_str_mv |
AT podderashiskumar qualitativeandquantitativeanalysisofsildenafilintraditionalmedicinesanddietarysupplements AT chakrobartyjayantakishor qualitativeandquantitativeanalysisofsildenafilintraditionalmedicinesanddietarysupplements AT faroqueabm qualitativeandquantitativeanalysisofsildenafilintraditionalmedicinesanddietarysupplements |
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1814309886857576448 |