The effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study
This article was published in the Bangladesh Journal of Microbiology and Development [© 2013] and The Journal's website is at:http://www.banglajol.info/index.php/BJM/article/view/28450
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© 2013 Bangladesh Journal of Microbiology
2016
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10361-68102016-11-15T06:25:22Z The effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study Mosharraf, Fahareen Binta Ahsan, Chowdhury Rafiqul Nessa, Jamalun Yasmin, Mahmuda Department of Mathematical and Natural Science, BRAC University E. coli 0157:H7 infection Streptomycin treated murine model This article was published in the Bangladesh Journal of Microbiology and Development [© 2013] and The Journal's website is at:http://www.banglajol.info/index.php/BJM/article/view/28450 Escherichia coli O157:H7 is a newly emerged pathogen, which has been recognized as a major cause of large scale epidemics and thousands of sporadic cases of gastrointestinal illness. This observation particularly calls for the in vivo examination of E. coli O157 candidates in an attempt to mimic various aspects of E. coli O157:H7 disease symptoms in humans. Healthy conventional Swiss albino mice were used for investigating the clinical manifestation exerted by stx1A and stx2A positive E. coli O157:H7 in various doses applied through three alternative routes (oral, intramuscular and intraperitoneal). The highest titer of orally added E. coli 0157:H7 (109 CFU ml-1) among the five test doses had started symptoms at the earliest time and manifested most of the classical symptoms. The symptoms started to become visible at 14th hour, increased with time and had reached moribund condition near 48th hour just before death of the host. The oral way of E. coli O157:H7 addition at the dose of 100 μl suspension containing 1 X 109CFU ml-1 was taken as the most potent concentration in producing bacterial fatality and hence was selected as the Minimum Lethal Dose (MLD). Published 2016-11-13T10:26:58Z 2016-11-13T10:26:58Z 2013-06 Article Mosharraf, F. B., Ahsan, C. R., Nessa, J., & Yasmin, M. (2013). The effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study. Bangladesh Journal of Microbiology, 30(1&2), 31–38. doi:http://dx.doi.org/10.3329/bjm.v30i1-2.28450 1011-9981 2408-8374 http://hdl.handle.net/10361/6810 en http://www.banglajol.info/index.php/BJM/article/view/28450 © 2013 Bangladesh Journal of Microbiology |
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Brac University |
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Institutional Repository |
| language |
English |
| topic |
E. coli 0157:H7 infection Streptomycin treated murine model |
| spellingShingle |
E. coli 0157:H7 infection Streptomycin treated murine model Mosharraf, Fahareen Binta Ahsan, Chowdhury Rafiqul Nessa, Jamalun Yasmin, Mahmuda The effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study |
| description |
This article was published in the Bangladesh Journal of Microbiology and Development [© 2013] and The Journal's website is at:http://www.banglajol.info/index.php/BJM/article/view/28450 |
| author2 |
Department of Mathematical and Natural Science, BRAC University |
| author_facet |
Department of Mathematical and Natural Science, BRAC University Mosharraf, Fahareen Binta Ahsan, Chowdhury Rafiqul Nessa, Jamalun Yasmin, Mahmuda |
| format |
Article |
| author |
Mosharraf, Fahareen Binta Ahsan, Chowdhury Rafiqul Nessa, Jamalun Yasmin, Mahmuda |
| author_sort |
Mosharraf, Fahareen Binta |
| title |
The effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study |
| title_short |
The effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study |
| title_full |
The effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study |
| title_fullStr |
The effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study |
| title_full_unstemmed |
The effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study |
| title_sort |
effect of verotoxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model: a longitudinal study |
| publisher |
© 2013 Bangladesh Journal of Microbiology |
| publishDate |
2016 |
| url |
http://hdl.handle.net/10361/6810 |
| work_keys_str_mv |
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