Exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model
This article was published in the Journal of Bangladesh Academy of Sciences [© 2015 ] and the The Journal's website is at: http://www.banglajol.info/index.php/JBAS/article/download/23658/16179.
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| Ngôn ngữ: | English |
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© 2015 Journal of Bangladesh Academy of Sciences
2016
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| Truy cập trực tuyến: | http://hdl.handle.net/10361/6788 |
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10361-6788 |
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10361-67882016-11-09T07:03:22Z Exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model Mosharraf, Fahareen-Binta Ahsan, Chowdhury Rafiqul Nessa, Jamalun Yasmin, Mahmuda Department of Mathematical and Natural Science, BRAC University E. coli 0157:H7 Bacteremia Blood and stool culture Murine model This article was published in the Journal of Bangladesh Academy of Sciences [© 2015 ] and the The Journal's website is at: http://www.banglajol.info/index.php/JBAS/article/download/23658/16179. The prevalence of Escherichia coli O157:H7 induced bacteremia generate a critical problem in modern medical therapy for bacterial infections. This study sought to find out the best possible route and dose of E. coli 0157:H7 infection in experimental murine model by periodic stool and blood culture count of relevant bacterial strains. Streptomycin treated mouse model were used for investigating the clinical manifestation exerted by stx1A and stx2A positive E. coli O157:H7 with increasing doses applied through three alternative routes (oral, intramuscular and intraperitoneal). The highest titer of orally added E. coli 0157:H7 among five test doses started showing symptoms at the earliest time and reached moribund condition about 48 hours just before being dead. The oral way of E.coli O157:H7 at the dose of 100 ƒÝl suspension containing 1 „e 109CFU ml-1 was taken as the most potent concentration in producing bacterial fatality and hence was selected as the minimum lethal dose (MLD). Published 2016-11-08T10:45:12Z 2016-11-08T10:45:12Z 2015 Article Mosharraf, F.-B., Ahsan, C. R., Nessa, J., & Yasmin, M. (2015). Exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model. Journal of Bangladesh Academy of Sciences, 39(1), 53–58. Retrieved from http://www.banglajol.info/index.php/JBAS/article/download/23658/16179. 0378-8121 http://hdl.handle.net/10361/6788 en http://www.banglajol.info/index.php/JBAS/article/download/23658/16179. © 2015 Journal of Bangladesh Academy of Sciences |
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Brac University |
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Institutional Repository |
| language |
English |
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E. coli 0157:H7 Bacteremia Blood and stool culture Murine model |
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E. coli 0157:H7 Bacteremia Blood and stool culture Murine model Mosharraf, Fahareen-Binta Ahsan, Chowdhury Rafiqul Nessa, Jamalun Yasmin, Mahmuda Exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model |
| description |
This article was published in the Journal of Bangladesh Academy of Sciences [© 2015 ] and the The Journal's website is at: http://www.banglajol.info/index.php/JBAS/article/download/23658/16179. |
| author2 |
Department of Mathematical and Natural Science, BRAC University |
| author_facet |
Department of Mathematical and Natural Science, BRAC University Mosharraf, Fahareen-Binta Ahsan, Chowdhury Rafiqul Nessa, Jamalun Yasmin, Mahmuda |
| format |
Article |
| author |
Mosharraf, Fahareen-Binta Ahsan, Chowdhury Rafiqul Nessa, Jamalun Yasmin, Mahmuda |
| author_sort |
Mosharraf, Fahareen-Binta |
| title |
Exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model |
| title_short |
Exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model |
| title_full |
Exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model |
| title_fullStr |
Exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model |
| title_full_unstemmed |
Exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model |
| title_sort |
exploring the best possible route of infection of verotxin producing escherichia coli in development of experimental gastroenteritis among streptomycin treated murine model |
| publisher |
© 2015 Journal of Bangladesh Academy of Sciences |
| publishDate |
2016 |
| url |
http://hdl.handle.net/10361/6788 |
| work_keys_str_mv |
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