Phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf
This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2015
| 主要作者: | |
|---|---|
| 其他作者: | |
| 格式: | Project report |
| 语言: | English |
| 出版: |
BRAC University
2015
|
| 主题: | |
| 在线阅读: | http://hdl.handle.net/10361/4662 |
| id |
10361-4662 |
|---|---|
| record_format |
dspace |
| spelling |
10361-46622019-09-30T04:08:48Z Phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf Nadi, Fatem-Tuz-Zohora Khair, Nishat Zareen Department of Pharmacy, BRAC University Pharmacy Phytochemical screening Membrane stabilizing Swietenia mahagony This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2015 Cataloged from PDF version of Internship report. Includes bibliographical references (page 51-53). Swietenia mahagony is such a medicinal plant that has numerous significant properties. Different parts of this plant such as bark, stem, leaves, trunk, seed, fruit and flower exert medicinal efficiency that can be incorporated to treat diverse ailments and can develop new formulas essential to treat newer afflictions. Swietenia mahagony leaves were focused in this study which was extracted with ethanol as a solvent. In the current study, ethanol extract was subjected to phyto-chemical screening, membrane stabilizing activity as well as brine shrimp lethality bioassay. Phyto-chemical screening was done by using distinct reagents intended for identifying primary and secondary phyto-chemicals such as tannins, flavonoids, alkaloids, carbohydrates, glucosides, glycosides, saponins etc. It was found from the analysis that ethanol extract of Swietenia mahagony leaves contains carbohydrates, saponins and tannins primarily. From the membrane stabilizing assay, where acetyl alicylic acid which is a well-known anti-inflammatory drug was employed as reference standard reported to have minimum membrane stabilizing effect while incorporated with ethanol extract of leaves of Swietenia mahagony. In case of brine shrimp lethality bioassay, the ethanol extract showed satisfactory cytotoxic effect that permits more sophisticated assay to be executed in the future. To conclude, it can be claimed, the results obtained from the experimental data were appreciating enough to run further studies considering different parameters such as using different solvent type- methanol, ethanol, acetone, chloroform etc, activity of the plant extract on to evaluate anti-diabetic, anti-malarial effect etc Fatem-Tuz-Zohora Nadi B. Pharmacy 2015-11-29T07:40:33Z 2015-11-29T07:40:33Z 2015 2015-08 Project report ID 11346002 http://hdl.handle.net/10361/4662 en BRAC University project report are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 53 pages application/pdf BRAC University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Pharmacy Phytochemical screening Membrane stabilizing Swietenia mahagony |
| spellingShingle |
Pharmacy Phytochemical screening Membrane stabilizing Swietenia mahagony Nadi, Fatem-Tuz-Zohora Phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf |
| description |
This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2015 |
| author2 |
Khair, Nishat Zareen |
| author_facet |
Khair, Nishat Zareen Nadi, Fatem-Tuz-Zohora |
| format |
Project report |
| author |
Nadi, Fatem-Tuz-Zohora |
| author_sort |
Nadi, Fatem-Tuz-Zohora |
| title |
Phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf |
| title_short |
Phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf |
| title_full |
Phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf |
| title_fullStr |
Phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf |
| title_full_unstemmed |
Phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf |
| title_sort |
phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf |
| publisher |
BRAC University |
| publishDate |
2015 |
| url |
http://hdl.handle.net/10361/4662 |
| work_keys_str_mv |
AT nadifatemtuzzohora phytochemicalscreeningmembranestabilizingactivityandcytotoxicityofethanolextractofswieteniamahagonyleaf |
| _version_ |
1814307457673986048 |