Study of the antimicrobial activities of the bark extract of cinnamomum verum on multi drug resistant klebsiella pneumoniae and enterobacter agglomerans
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2015
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BRAC University
2015
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10361-44402019-09-30T04:12:42Z Study of the antimicrobial activities of the bark extract of cinnamomum verum on multi drug resistant klebsiella pneumoniae and enterobacter agglomerans Mahmud-Un-Nabi, Mohammad Al Mannoor, Dr. Md. Kaiissar Hossain, Dr. Mahboob Department of Mathematical and Natural Science, BRAC University Microbiology Antimicrobial Klebsiella pneumoniae Enterobacter agglomerans Cinnamomum verum This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2015 Cataloged from PDF version of thesis report. Includes bibliographical references (page 39-40). Infections caused by Multi Drug Resistant (MDR) organisms cause to stand a worldwide pandemic. MDR bacteria are an emerging threat with limited therapeutic options. Without having information about these strains, morbidity and mortality due to infections caused by these notorious bugs cannot be reduced. Alternative antimicrobial agent is needed beside the antibiotics to combat against these MDR organisms. Cinnamon is a spice obtained from the inner bark of trees of Cinnamomum sp. Traditionally it has also been used for medicinal purposes. In the current work we evaluated the antimicrobial activity of the cinnamon extract against MDR Klebsiella pneumoniae and Enterobacter aggalomerans, and also compared the results with drug sensitive organisms of the same species. Cinnamon extract was prepared with ethanol extraction procedure. The extract was dried and re-dissolved in Dimethyl sulfoxide (DMSO). The prepared extract was tested on the organisms by using agar diffusion technique followed by determination of Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the cinnamon extract. From the agar diffusion test the minimum concentration of cinnamon extracts needed to visualise the zone of inhibition on the Mueller Hinton Agar was determined to be 40 mg/ml. The MIC of the cinnamon extract was found to be 1 mg/ml and the MBC was determined as 2 mg/ml. The results obtained from this study can act as the stepping stone in investigating the antimicrobial properties of cinnamon extract. This study could be the beginning of discovering a new antimicrobial agent against the MDR organisms. Mohammad Al Mahmud-Un-Nabi B. Microbiology 2015-09-23T06:30:13Z 2015-09-23T06:30:13Z 2015 2015-08 Thesis ID 11326004 http://hdl.handle.net/10361/4440 en BRAC University thesis are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 40 pages application/pdf BRAC University |
institution |
Brac University |
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Institutional Repository |
language |
English |
topic |
Microbiology Antimicrobial Klebsiella pneumoniae Enterobacter agglomerans Cinnamomum verum |
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Microbiology Antimicrobial Klebsiella pneumoniae Enterobacter agglomerans Cinnamomum verum Mahmud-Un-Nabi, Mohammad Al Study of the antimicrobial activities of the bark extract of cinnamomum verum on multi drug resistant klebsiella pneumoniae and enterobacter agglomerans |
description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2015 |
author2 |
Mannoor, Dr. Md. Kaiissar |
author_facet |
Mannoor, Dr. Md. Kaiissar Mahmud-Un-Nabi, Mohammad Al |
format |
Thesis |
author |
Mahmud-Un-Nabi, Mohammad Al |
author_sort |
Mahmud-Un-Nabi, Mohammad Al |
title |
Study of the antimicrobial activities of the bark extract of cinnamomum verum on multi drug resistant klebsiella pneumoniae and enterobacter agglomerans |
title_short |
Study of the antimicrobial activities of the bark extract of cinnamomum verum on multi drug resistant klebsiella pneumoniae and enterobacter agglomerans |
title_full |
Study of the antimicrobial activities of the bark extract of cinnamomum verum on multi drug resistant klebsiella pneumoniae and enterobacter agglomerans |
title_fullStr |
Study of the antimicrobial activities of the bark extract of cinnamomum verum on multi drug resistant klebsiella pneumoniae and enterobacter agglomerans |
title_full_unstemmed |
Study of the antimicrobial activities of the bark extract of cinnamomum verum on multi drug resistant klebsiella pneumoniae and enterobacter agglomerans |
title_sort |
study of the antimicrobial activities of the bark extract of cinnamomum verum on multi drug resistant klebsiella pneumoniae and enterobacter agglomerans |
publisher |
BRAC University |
publishDate |
2015 |
url |
http://hdl.handle.net/10361/4440 |
work_keys_str_mv |
AT mahmudunnabimohammadal studyoftheantimicrobialactivitiesofthebarkextractofcinnamomumverumonmultidrugresistantklebsiellapneumoniaeandenterobacteragglomerans |
_version_ |
1814307689031794688 |