In vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulp
This project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.
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10361-243852024-10-22T21:03:20Z In vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulp Karim, Tahira Ripa, Farhana Alam School of Pharmacy, Brac University Nypa fruticans wurmb NFS Antidiarrheal activity Diarrheal disease Diarrhea treatment Antidiarrheal agents Diarrhea--treatment. Plant extracts--Therapeutic use. Fruits--Therapeutic use. Medicinal plants. Antidiarrheals. This project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024. Cataloged from PDF version of project report. Includes bibliographical references (pages 24-30). Nypa fruticans wurmb has long been utilized in traditional medicine to treat a variety of illnesses including diarrhea. The study was conducted to evaluate antidiarrheal property of the methanolic fruit pulp extract of N. fruticans (NFS). The antidiarrheal activity of NFS extract tested in an experimental model (Swiss albino mice) of castor oil induced diarrhea in 3 different doses- 200, 400 and 600 mg/kg. A significant (p<0.5) reduction in the frequency of wet stools and delaying the onset of diarrhea as compared with the control group were observed in rodents treated with the methanolic crude extract at doses 400 and 600 mg/kg. However, the effect of increased dose dependently and 600 mg/kg NFS extract produced a comparable effect (66.68%) with the reference drug (Loperamide) in mice. Therefore our result proved that N. fruticans (NFS) has potent antidiarrheal activity. Moreover the investigation's promising findings may provide a framework for further study in this area. Tahira Karim B. Pharmacy 2024-10-22T08:32:11Z 2024-10-22T08:32:11Z ©2024 2024-02 Project report ID 20146045 http://hdl.handle.net/10361/24385 en Brac University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 43 pages application/pdf Brac University |
institution |
Brac University |
collection |
Institutional Repository |
language |
English |
topic |
Nypa fruticans wurmb NFS Antidiarrheal activity Diarrheal disease Diarrhea treatment Antidiarrheal agents Diarrhea--treatment. Plant extracts--Therapeutic use. Fruits--Therapeutic use. Medicinal plants. Antidiarrheals. |
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Nypa fruticans wurmb NFS Antidiarrheal activity Diarrheal disease Diarrhea treatment Antidiarrheal agents Diarrhea--treatment. Plant extracts--Therapeutic use. Fruits--Therapeutic use. Medicinal plants. Antidiarrheals. Karim, Tahira In vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulp |
description |
This project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024. |
author2 |
Ripa, Farhana Alam |
author_facet |
Ripa, Farhana Alam Karim, Tahira |
format |
Project report |
author |
Karim, Tahira |
author_sort |
Karim, Tahira |
title |
In vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulp |
title_short |
In vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulp |
title_full |
In vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulp |
title_fullStr |
In vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulp |
title_full_unstemmed |
In vivo antidiarrheal activity of Nypa fruticans wurmb fruit pulp |
title_sort |
in vivo antidiarrheal activity of nypa fruticans wurmb fruit pulp |
publisher |
Brac University |
publishDate |
2024 |
url |
http://hdl.handle.net/10361/24385 |
work_keys_str_mv |
AT karimtahira invivoantidiarrhealactivityofnypafruticanswurmbfruitpulp |
_version_ |
1814308579688054784 |