Investigation of in vivo antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli leaf extract
A thesis submitted to the School of Pharmacy in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.
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Định dạng: | Luận văn |
Ngôn ngữ: | English |
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Brac University
2024
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Truy cập trực tuyến: | http://hdl.handle.net/10361/24022 |
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10361-240222024-09-10T10:49:07Z Investigation of in vivo antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli leaf extract Rajib, Raisha Akter, Raushanara School of Pharmacy Medicinal plant Lagerstroemia thorelli CNS depressant antidiabetic Central nervous system depressants. Analgesics. A thesis submitted to the School of Pharmacy in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024. Cataloged from PDF version of thesis. Includes bibliographical references (pages 35-40). Plants in the Lythraceae family are well-known for having anti-inflammatory, analgesic, and antidiabetic qualities. However, through a comprehensive literature search it was found that the antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli (L. thorelli) have not yet been investigated. This research involved the use of the ethanol leaf extract of Lagerstroemia thorelli at doses of 200 mg/kg, 400 mg/kg, and 600 mg/kg in Swiss albino mice. The antidiabetic effect was assessed in alloxan-induced diabetic mice, the analgesic activity was detected using the acetic acid-induced writhing test, and the CNS depressant effect was determined using the hole cross method. The plant extract exhibited a dose-dependent, statistically significant (P<0.01) antidiabetic, remarkable analgesic and CNS depressant properties. Thus, the present study suggests that extract of Lagerstroemia thorelli could be an effective treatment for diabetes. Raisha Rajib Bachelor of Pharmacy 2024-09-09T03:39:28Z 2024-09-09T03:39:28Z © 2024 2024-04 Thesis ID 20146011 http://hdl.handle.net/10361/24022 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 40 pages application/pdf Brac University |
institution |
Brac University |
collection |
Institutional Repository |
language |
English |
topic |
Medicinal plant Lagerstroemia thorelli CNS depressant antidiabetic Central nervous system depressants. Analgesics. |
spellingShingle |
Medicinal plant Lagerstroemia thorelli CNS depressant antidiabetic Central nervous system depressants. Analgesics. Rajib, Raisha Investigation of in vivo antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli leaf extract |
description |
A thesis submitted to the School of Pharmacy in partial fulfillment of the requirements for
the degree of Bachelor of Pharmacy, 2024. |
author2 |
Akter, Raushanara |
author_facet |
Akter, Raushanara Rajib, Raisha |
format |
Thesis |
author |
Rajib, Raisha |
author_sort |
Rajib, Raisha |
title |
Investigation of in vivo antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli leaf extract |
title_short |
Investigation of in vivo antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli leaf extract |
title_full |
Investigation of in vivo antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli leaf extract |
title_fullStr |
Investigation of in vivo antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli leaf extract |
title_full_unstemmed |
Investigation of in vivo antidiabetic, analgesic, and CNS depressant properties of Lagerstroemia thorelli leaf extract |
title_sort |
investigation of in vivo antidiabetic, analgesic, and cns depressant properties of lagerstroemia thorelli leaf extract |
publisher |
Brac University |
publishDate |
2024 |
url |
http://hdl.handle.net/10361/24022 |
work_keys_str_mv |
AT rajibraisha investigationofinvivoantidiabeticanalgesicandcnsdepressantpropertiesoflagerstroemiathorellileafextract |
_version_ |
1814307957907652608 |