Inhibition of acinetobacter baumannii biofilm formation by black pepper extract
This thesis submitted to the Department of Mathematics and Natural Sciences in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology, 2024.
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| Langue: | English |
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Brac University
2024
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| Accès en ligne: | http://hdl.handle.net/10361/23993 |
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10361-239932024-09-11T07:41:42Z Inhibition of acinetobacter baumannii biofilm formation by black pepper extract Rahman, Nafin Tanni, Rounok Jahan Reza, Setuli Hossain, M. Mahboob Department of Mathematics and Natural Sciences, Brac University Acinetobacter baumannii Biofilm formation Black pepper Acinetobacter infections. This thesis submitted to the Department of Mathematics and Natural Sciences in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology, 2024. Cataloged from PDF version of thesis. Includes bibliographical references (pages 39-41). Acinetobacter baumannii, a Gram-negative opportunistic pathogen, is considered a significant concern in clinical aspects due to its ability to form biofilms and its resistance to multiple antibiotics. This study aims to evaluate the inhibitory effect of Black Pepper Extract on Acinetobacter baumannii biofilm formation. The clinical isolates of A. baumannii were collected from patients at the National Institute of Traumatology and Orthopedic Rehabilitation (NITOR) and identified using physical and molecular methods such as Colony morphology pattern, Gram staining technique, and PCR confirmation. An antibiotic susceptibility test (AST) was also conducted which showed that the strain was resistant to multiple antibiotics including ampicillin- sulbactam, amoxicillin, and ceftazidime. In this study, various biofilm formation tests such as: Congo Red Agar (CRA) method, tube method, and Tissue Culture Plate (TCP) method were employed to find the potential of black pepper extract in the inhibition biofilm formation. The findings indicate that black pepper extract exhibits significant anti-biofilm activity, which can be used as a non-antibiotic strategy to combat biofilm-related infections caused by Acinetobacter baumannii. Md Nafin Rahman Rounok Jahan Tanni Setuli Reza B. Biotechnology 2024-09-08T03:40:58Z 2024-09-08T03:40:58Z ©2024 2024-08 Thesis ID 19336024 ID 19336013 ID 19336008 http://hdl.handle.net/10361/23993 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 41 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Acinetobacter baumannii Biofilm formation Black pepper Acinetobacter infections. |
| spellingShingle |
Acinetobacter baumannii Biofilm formation Black pepper Acinetobacter infections. Rahman, Nafin Tanni, Rounok Jahan Reza, Setuli Inhibition of acinetobacter baumannii biofilm formation by black pepper extract |
| description |
This thesis submitted to the Department of Mathematics and Natural Sciences in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology, 2024. |
| author2 |
Hossain, M. Mahboob |
| author_facet |
Hossain, M. Mahboob Rahman, Nafin Tanni, Rounok Jahan Reza, Setuli |
| format |
Thesis |
| author |
Rahman, Nafin Tanni, Rounok Jahan Reza, Setuli |
| author_sort |
Rahman, Nafin |
| title |
Inhibition of acinetobacter baumannii biofilm formation by black pepper extract |
| title_short |
Inhibition of acinetobacter baumannii biofilm formation by black pepper extract |
| title_full |
Inhibition of acinetobacter baumannii biofilm formation by black pepper extract |
| title_fullStr |
Inhibition of acinetobacter baumannii biofilm formation by black pepper extract |
| title_full_unstemmed |
Inhibition of acinetobacter baumannii biofilm formation by black pepper extract |
| title_sort |
inhibition of acinetobacter baumannii biofilm formation by black pepper extract |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/23993 |
| work_keys_str_mv |
AT rahmannafin inhibitionofacinetobacterbaumanniibiofilmformationbyblackpepperextract AT tannirounokjahan inhibitionofacinetobacterbaumanniibiofilmformationbyblackpepperextract AT rezasetuli inhibitionofacinetobacterbaumanniibiofilmformationbyblackpepperextract |
| _version_ |
1814309597792436224 |