Targeting DHFR in breast cancer: exploring expression patterns and identifying potential inhibitors through docking studies

Targeting DHFR in breast cancer: exploring expression patterns and identifying potential inhibitors through docking studies

This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.

Bibliografiska uppgifter
Huvudupphovsman:	Araf, Faiaz Fahim
Övriga upphovsmän:	Mustafa, Nashrah
Materialtyp:	Lärdomsprov
Språk:	English
Publicerad:	Brac University 2024
Ämnen:	Dihydrofolate reductase Breast cancer DHFR expression Molecular docking Breast > Cancer Drugs > Computer-aided design
Länkar:	http://hdl.handle.net/10361/23949

Liknande verk

Breast cancer awareness seminars
av: Anwer Khan Modern Medical College
Publicerad: (2016)

Recent advancement on breast cancer detection and treatment
av: Rahman, Sanjida
Publicerad: (2023)

In silico analysis revealed hsa-miR-19a-3p and hsa-miR-19b-3p as two potential inhibitors of EGF mRNA in Breast Cancer
av: Nuha, Nabiha Tahsin
Publicerad: (2024)

Natural products and their combinatory effects in breast cancer treatment
av: Siddique, Md. Ayman
Publicerad: (2021)

Targeted therapeutic options in the treatment of Breast Cancer
av: Alam, Kazi Tasnuva
Publicerad: (2022)

Drug repurposing: potential of Antimicrobial Drugs in Breast Cancer Treatment
av: Chakraborty, Anuradha
Publicerad: (2024)

A review on triple-negative breast cancer and its potential treatment
av: Niasa, Jannatul Ferdous
Publicerad: (2023)

Pooled analysis of progression-free survival and overall survival in phase II clinical trials of breast cancer
av: Shobnam, Sohana
Publicerad: (2024)

A review of Breast Cancer risk factor assessment on women in developing countries, cancer drug resistance, and Breast Cancer treatment in Bangladesh
av: Raihan, Dilraj
Publicerad: (2024)

The impact of breast cancer on women’s lives in Bangladesh
av: Mobashera, Tayeeba Tum
Publicerad: (2024)

Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review
av: Akter, Honufa
Publicerad: (2024)

Machine learning as an indicator for breast cancer prediction
av: Shadman, Tahsin Mohammed, et al.
Publicerad: (2019)

Breast cancer in low-resource settings: Prioritizing the awareness and access programmes to overcome sociocultural and economic barriers for early detection and improved outcomes
av: Iqbal, Mohammad Shamim, et al.
Publicerad: (2017)

Breast cancer therapy through Liposomal drug delivery system
av: Ome, Nusrat Jahan
Publicerad: (2024)

Pathway analysis of Disease-Gene associated network in the human breast cancer
av: Lamia
Publicerad: (2020)

A review on the potential of repurposing of metformin for colon cancer and breast cancer
av: Oishy, Jannatun Noor
Publicerad: (2024)

Early detection of breast cancer using machine learning
av: Fuad, Wasi Mohammad
Publicerad: (2019)

Breast cancer in South Asia: a Bangladeshi perspective
av: Hossain, Mohammad Sorowar, et al.
Publicerad: (2017)

Tamoxifen: The ideal post operative hormonal therapy to demote Ductal Carcinoma in Situ
av: Mirza, Maisa Tasnim
Publicerad: (2023)

Breast cancer prediction using different machine learning models
av: Khandker Al- Muhaimin, et al.
Publicerad: (2020)

Association of BRCA1, BRCA2, RAD51, and HER2 gene polymorphisms with the breast cancer risk in the Bangladeshi population
av: Parvin, Salma, et al.
Publicerad: (2016)

InSilico structure based designing of dihydrofolate reductase enzyme antagonists and potential small molecules that target DHFR protein to inhibit the folic acid biosynthetic pathways
av: Hossain, Md. Sameer
Publicerad: (2018)

Inhibition of Fibroblast Activation Protein alpha (FAP-α) in Colorectal Cancer
av: Tabassum, Azwada
Publicerad: (2021)

Computational insights into molecular docking strategies for non-small cell lung cancer drug discovery
av: Das, Reshita
Publicerad: (2024)

Genetic innovations for breast cancer treatment : a review of gene therapy strategies and future implications
av: Hasan, Sakib
Publicerad: (2024)

Machine learning In breast cancer prognosis and prediction
av: Chowdhury, Shah Abul Hasnat, et al.
Publicerad: (2023)

A review on newly approved PARP inhibitors: Talazoparib and Olaparib
av: Karim, Azrin
Publicerad: (2024)

Use of combination of satins as antagonists of SPARC in stomach cancer: an in silico study
av: Rashed, Sadman Sakib Bin
Publicerad: (2019)

A review on principles of molecular docking and its application in drug discovery
av: Sharif Ezzaz, Ahamed
Publicerad: (2024)

Heat shock protein: potential approach for chemotherapy
av: Sykut, Md. Rezaul Hoque
Publicerad: (2022)

Bioinformatics analyses of key regulators of NF-κB pathway in relation with small cell lung carcinoma
av: Zangmo, Thinley
Publicerad: (2024)

A review on potential of PARP inhibitors in the treatment of prostate cancer
av: Islam, Saidul
Publicerad: (2022)

Molecules associated with the development of lung cancer
av: Rahman, Adree, et al.
Publicerad: (2023)

SHP2 inhibitors: Recent advancements and potential breakthroughs in cancer therapy
av: Meem, Manila
Publicerad: (2023)

Molecular biology of cancer : mechanisms, targets, and therapeutics /
av: Pecorino, Lauren
Publicerad: (2012)

Application of deep convolutional neural network in breast cancer prediction using Digital Mammograms
av: Al Mamun, Rafsan, et al.
Publicerad: (2022)

Molecular docking of Fluvastatin and Teneligliptin targeting AT1R in hypertension
av: Jahan, Esrat
Publicerad: (2020)

Automatic docking system using sonar
av: Akther, Rabeya, et al.
Publicerad: (2015)

Best feature selection and data visualization for breast cancer prediction
av: Hemel, Tanjim Ahmed, et al.
Publicerad: (2020)

Statistics and informatics in molecular cancer research