Targeting DHFR in breast cancer: exploring expression patterns and identifying potential inhibitors through docking studies

Targeting DHFR in breast cancer: exploring expression patterns and identifying potential inhibitors through docking studies

This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.

Dades bibliogràfiques
Autor principal:	Araf, Faiaz Fahim
Altres autors:	Mustafa, Nashrah
Format:	Thesis
Idioma:	English
Publicat:	Brac University 2024
Matèries:	Dihydrofolate reductase Breast cancer DHFR expression Molecular docking Breast > Cancer Drugs > Computer-aided design
Accés en línia:	http://hdl.handle.net/10361/23949

Ítems similars

Breast cancer awareness seminars
per: Anwer Khan Modern Medical College
Publicat: (2016)

Recent advancement on breast cancer detection and treatment
per: Rahman, Sanjida
Publicat: (2023)

In silico analysis revealed hsa-miR-19a-3p and hsa-miR-19b-3p as two potential inhibitors of EGF mRNA in Breast Cancer
per: Nuha, Nabiha Tahsin
Publicat: (2024)

Natural products and their combinatory effects in breast cancer treatment
per: Siddique, Md. Ayman
Publicat: (2021)

Targeted therapeutic options in the treatment of Breast Cancer
per: Alam, Kazi Tasnuva
Publicat: (2022)

Drug repurposing: potential of Antimicrobial Drugs in Breast Cancer Treatment
per: Chakraborty, Anuradha
Publicat: (2024)

A review on triple-negative breast cancer and its potential treatment
per: Niasa, Jannatul Ferdous
Publicat: (2023)

Pooled analysis of progression-free survival and overall survival in phase II clinical trials of breast cancer
per: Shobnam, Sohana
Publicat: (2024)

A review of Breast Cancer risk factor assessment on women in developing countries, cancer drug resistance, and Breast Cancer treatment in Bangladesh
per: Raihan, Dilraj
Publicat: (2024)

The impact of breast cancer on women’s lives in Bangladesh
per: Mobashera, Tayeeba Tum
Publicat: (2024)

Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review
per: Akter, Honufa
Publicat: (2024)

Machine learning as an indicator for breast cancer prediction
per: Shadman, Tahsin Mohammed, et al.
Publicat: (2019)

Breast cancer in low-resource settings: Prioritizing the awareness and access programmes to overcome sociocultural and economic barriers for early detection and improved outcomes
per: Iqbal, Mohammad Shamim, et al.
Publicat: (2017)

Breast cancer therapy through Liposomal drug delivery system
per: Ome, Nusrat Jahan
Publicat: (2024)

Pathway analysis of Disease-Gene associated network in the human breast cancer
per: Lamia
Publicat: (2020)

A review on the potential of repurposing of metformin for colon cancer and breast cancer
per: Oishy, Jannatun Noor
Publicat: (2024)

Early detection of breast cancer using machine learning
per: Fuad, Wasi Mohammad
Publicat: (2019)

Breast cancer in South Asia: a Bangladeshi perspective
per: Hossain, Mohammad Sorowar, et al.
Publicat: (2017)

Tamoxifen: The ideal post operative hormonal therapy to demote Ductal Carcinoma in Situ
per: Mirza, Maisa Tasnim
Publicat: (2023)

Breast cancer prediction using different machine learning models
per: Khandker Al- Muhaimin, et al.
Publicat: (2020)

Association of BRCA1, BRCA2, RAD51, and HER2 gene polymorphisms with the breast cancer risk in the Bangladeshi population
per: Parvin, Salma, et al.
Publicat: (2016)

InSilico structure based designing of dihydrofolate reductase enzyme antagonists and potential small molecules that target DHFR protein to inhibit the folic acid biosynthetic pathways
per: Hossain, Md. Sameer
Publicat: (2018)

Inhibition of Fibroblast Activation Protein alpha (FAP-α) in Colorectal Cancer
per: Tabassum, Azwada
Publicat: (2021)

Computational insights into molecular docking strategies for non-small cell lung cancer drug discovery
per: Das, Reshita
Publicat: (2024)

Genetic innovations for breast cancer treatment : a review of gene therapy strategies and future implications
per: Hasan, Sakib
Publicat: (2024)

Machine learning In breast cancer prognosis and prediction
per: Chowdhury, Shah Abul Hasnat, et al.
Publicat: (2023)

A review on newly approved PARP inhibitors: Talazoparib and Olaparib
per: Karim, Azrin
Publicat: (2024)

Use of combination of satins as antagonists of SPARC in stomach cancer: an in silico study
per: Rashed, Sadman Sakib Bin
Publicat: (2019)

A review on principles of molecular docking and its application in drug discovery
per: Sharif Ezzaz, Ahamed
Publicat: (2024)

Heat shock protein: potential approach for chemotherapy
per: Sykut, Md. Rezaul Hoque
Publicat: (2022)

Bioinformatics analyses of key regulators of NF-κB pathway in relation with small cell lung carcinoma
per: Zangmo, Thinley
Publicat: (2024)

A review on potential of PARP inhibitors in the treatment of prostate cancer
per: Islam, Saidul
Publicat: (2022)

Molecules associated with the development of lung cancer
per: Rahman, Adree, et al.
Publicat: (2023)

SHP2 inhibitors: Recent advancements and potential breakthroughs in cancer therapy
per: Meem, Manila
Publicat: (2023)

Molecular biology of cancer : mechanisms, targets, and therapeutics /
per: Pecorino, Lauren
Publicat: (2012)

Application of deep convolutional neural network in breast cancer prediction using Digital Mammograms
per: Al Mamun, Rafsan, et al.
Publicat: (2022)

Molecular docking of Fluvastatin and Teneligliptin targeting AT1R in hypertension
per: Jahan, Esrat
Publicat: (2020)

Automatic docking system using sonar
per: Akther, Rabeya, et al.
Publicat: (2015)

Best feature selection and data visualization for breast cancer prediction
per: Hemel, Tanjim Ahmed, et al.
Publicat: (2020)

Statistics and informatics in molecular cancer research