Comparative efficacy of Sorafenib, and Lenvatinib in Hepatocellular Carcinoma: a meta-analysis
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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Brac University
2024
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| Rochtain ar líne: | http://hdl.handle.net/10361/23930 |
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10361-239302024-09-03T10:13:10Z Comparative efficacy of Sorafenib, and Lenvatinib in Hepatocellular Carcinoma: a meta-analysis Monayem, Kazi Fahim Momtaz, Tanisha School of Pharmacy, Brac University Hepatocellular carcinoma Lenvatinib Sorafenib Demographic analysis Clinical decision making Randomized controlled trials Progression-free survival Liver--Cancer--Treatment. Cancer--Molecular aspects. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from the PDF version of thesis. Includes bibliographical references (pages 33-35). Hepatocellular carcinoma (HCC) is an important healthcare problem with developing therapeutic options. This meta-analysis evaluates the effectiveness and safety of lenvatinib and sorafenib, focusing largely on overall survival, progression-free survival, and adverse events. Both drugs promote overall and progression-free survival; however, lenvatinib outperforms the other in the latter regard. There are differences in safety profiles; sorafenib has larger confidence intervals and more prominent effects. Publication bias is negligible. Due to demographic considerations, care should be used when applying these results to different groups of people. This analysis contributes to our understanding of the therapeutic options for HCC by providing insightful information that researchers and healthcare providers may use when deciding on an option of treatment. Kazi Fahim Monayem B. Pharmacy 2024-08-28T06:30:02Z 2024-08-28T06:30:02Z ©2023 2023-11 Thesis ID 18346083 http://hdl.handle.net/10361/23930 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 49 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Hepatocellular carcinoma Lenvatinib Sorafenib Demographic analysis Clinical decision making Randomized controlled trials Progression-free survival Liver--Cancer--Treatment. Cancer--Molecular aspects. |
| spellingShingle |
Hepatocellular carcinoma Lenvatinib Sorafenib Demographic analysis Clinical decision making Randomized controlled trials Progression-free survival Liver--Cancer--Treatment. Cancer--Molecular aspects. Monayem, Kazi Fahim Comparative efficacy of Sorafenib, and Lenvatinib in Hepatocellular Carcinoma: a meta-analysis |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Momtaz, Tanisha |
| author_facet |
Momtaz, Tanisha Monayem, Kazi Fahim |
| format |
Thesis |
| author |
Monayem, Kazi Fahim |
| author_sort |
Monayem, Kazi Fahim |
| title |
Comparative efficacy of Sorafenib, and Lenvatinib in Hepatocellular Carcinoma: a meta-analysis |
| title_short |
Comparative efficacy of Sorafenib, and Lenvatinib in Hepatocellular Carcinoma: a meta-analysis |
| title_full |
Comparative efficacy of Sorafenib, and Lenvatinib in Hepatocellular Carcinoma: a meta-analysis |
| title_fullStr |
Comparative efficacy of Sorafenib, and Lenvatinib in Hepatocellular Carcinoma: a meta-analysis |
| title_full_unstemmed |
Comparative efficacy of Sorafenib, and Lenvatinib in Hepatocellular Carcinoma: a meta-analysis |
| title_sort |
comparative efficacy of sorafenib, and lenvatinib in hepatocellular carcinoma: a meta-analysis |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/23930 |
| work_keys_str_mv |
AT monayemkazifahim comparativeefficacyofsorafenibandlenvatinibinhepatocellularcarcinomaametaanalysis |
| _version_ |
1814308274951946240 |