Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2024.
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10361-237502024-08-13T21:03:05Z Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract Mahi, Harun Al Islam, Hasan Samin Hossain, M. Mahboob Department of Mathematics and Natural Sciences, Brac University Holarrhena pubescens Antioxidant Antibacterial properties This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2024. Catalogued from PDF version of thesis. Includes bibliographical references (pages 37-40). The use of plants and their derivatives for therapeutic purposes dates back to the beginning of human civilization. Holarrhena pubescens, commonly known as "kurchi," is a medicinal plant recognized for its diverse therapeutic properties. This study investigates the antibacterial and antioxidant potentials of Holarrhena pubescens bark extracts. Antioxidant activity was evaluated using the DPPH assay. The free radical scavenging activities of the extracts ranged from very strong to strong, with chloroform extracts showing the lowest IC50 value of 15.59 μg/ml and ethyl acetate extracts showing the highest at 157.14 μg/ml. All partitioned extracts demonstrated significant potential as antioxidants, given that IC50 values below 50 indicate very strong activity. Contrarily, the antibacterial tests indicated that Holarrhena pubescens lacks antibacterial properties. Despite this, the plant’s potent antioxidant capabilities merit further investigation. Future research should focus on the isolation of pure compounds using column chromatography and explore the plant’s potential anticancer properties. These findings underscore the therapeutic promise of Holarrhena pubescens, particularly its antioxidant activity, which could lead to the development of new, effective medicinal drugs. Further in-depth studies are necessary to fully elucidate the plant’s bioactive compounds and their possible applications in medicine. Harun Al Mahi Hasan Samin Islam B. Microbiology 2024-08-13T06:16:15Z 2024-08-13T06:16:15Z 2024 2024-06 Thesis ID 20126006 ID 20126015 http://hdl.handle.net/10361/23750 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 40 pages application/pdf Brac University |
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Brac University |
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Institutional Repository |
language |
English |
topic |
Holarrhena pubescens Antioxidant Antibacterial properties |
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Holarrhena pubescens Antioxidant Antibacterial properties Mahi, Harun Al Islam, Hasan Samin Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract |
description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2024. |
author2 |
Hossain, M. Mahboob |
author_facet |
Hossain, M. Mahboob Mahi, Harun Al Islam, Hasan Samin |
format |
Thesis |
author |
Mahi, Harun Al Islam, Hasan Samin |
author_sort |
Mahi, Harun Al |
title |
Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract |
title_short |
Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract |
title_full |
Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract |
title_fullStr |
Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract |
title_full_unstemmed |
Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract |
title_sort |
antibacterial and antioxidant properties of holarrhena pubescens (bangla name- “kurchi”) bark crude extract |
publisher |
Brac University |
publishDate |
2024 |
url |
http://hdl.handle.net/10361/23750 |
work_keys_str_mv |
AT mahiharunal antibacterialandantioxidantpropertiesofholarrhenapubescensbanglanamekurchibarkcrudeextract AT islamhasansamin antibacterialandantioxidantpropertiesofholarrhenapubescensbanglanamekurchibarkcrudeextract |
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