Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract

This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2024.

書目詳細資料
Main Authors: Mahi, Harun Al, Islam, Hasan Samin
其他作者: Hossain, M. Mahboob
格式: Thesis
語言:English
出版: Brac University 2024
主題:
在線閱讀:http://hdl.handle.net/10361/23750
id 10361-23750
record_format dspace
spelling 10361-237502024-08-13T21:03:05Z Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract Mahi, Harun Al Islam, Hasan Samin Hossain, M. Mahboob Department of Mathematics and Natural Sciences, Brac University Holarrhena pubescens Antioxidant Antibacterial properties This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2024. Catalogued from PDF version of thesis. Includes bibliographical references (pages 37-40). The use of plants and their derivatives for therapeutic purposes dates back to the beginning of human civilization. Holarrhena pubescens, commonly known as "kurchi," is a medicinal plant recognized for its diverse therapeutic properties. This study investigates the antibacterial and antioxidant potentials of Holarrhena pubescens bark extracts. Antioxidant activity was evaluated using the DPPH assay. The free radical scavenging activities of the extracts ranged from very strong to strong, with chloroform extracts showing the lowest IC50 value of 15.59 μg/ml and ethyl acetate extracts showing the highest at 157.14 μg/ml. All partitioned extracts demonstrated significant potential as antioxidants, given that IC50 values below 50 indicate very strong activity. Contrarily, the antibacterial tests indicated that Holarrhena pubescens lacks antibacterial properties. Despite this, the plant’s potent antioxidant capabilities merit further investigation. Future research should focus on the isolation of pure compounds using column chromatography and explore the plant’s potential anticancer properties. These findings underscore the therapeutic promise of Holarrhena pubescens, particularly its antioxidant activity, which could lead to the development of new, effective medicinal drugs. Further in-depth studies are necessary to fully elucidate the plant’s bioactive compounds and their possible applications in medicine. Harun Al Mahi Hasan Samin Islam B. Microbiology 2024-08-13T06:16:15Z 2024-08-13T06:16:15Z 2024 2024-06 Thesis ID 20126006 ID 20126015 http://hdl.handle.net/10361/23750 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 40 pages application/pdf Brac University
institution Brac University
collection Institutional Repository
language English
topic Holarrhena pubescens
Antioxidant
Antibacterial properties
spellingShingle Holarrhena pubescens
Antioxidant
Antibacterial properties
Mahi, Harun Al
Islam, Hasan Samin
Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract
description This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2024.
author2 Hossain, M. Mahboob
author_facet Hossain, M. Mahboob
Mahi, Harun Al
Islam, Hasan Samin
format Thesis
author Mahi, Harun Al
Islam, Hasan Samin
author_sort Mahi, Harun Al
title Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract
title_short Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract
title_full Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract
title_fullStr Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract
title_full_unstemmed Antibacterial and antioxidant properties of Holarrhena pubescens (Bangla name- “Kurchi”) Bark Crude extract
title_sort antibacterial and antioxidant properties of holarrhena pubescens (bangla name- “kurchi”) bark crude extract
publisher Brac University
publishDate 2024
url http://hdl.handle.net/10361/23750
work_keys_str_mv AT mahiharunal antibacterialandantioxidantpropertiesofholarrhenapubescensbanglanamekurchibarkcrudeextract
AT islamhasansamin antibacterialandantioxidantpropertiesofholarrhenapubescensbanglanamekurchibarkcrudeextract
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