Assessment of CNS depressant activity of Nypa Fruticans Wurmb fruit pulp
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.
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Brac University
2024
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| Rochtain ar líne: | http://hdl.handle.net/10361/23696 |
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10361-236962024-07-15T21:03:28Z Assessment of CNS depressant activity of Nypa Fruticans Wurmb fruit pulp Anika, Tasmim Farhana Ripa, Farhana Alam School of Pharmacy, Brac University Nypa fruticans Wurmb Nipa palm CNS depressant Diazepam Hole cross test Medicinal plants Herbs--Therapeutic use This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024. Cataloged from the PDF version of thesis. Includes bibliographical references (pages 59-63). Nypa fruticans Wurmb (Family: Arecaceae) or Nipa palm is locally known as “Golfol” in Bangladesh which is of great interest now for its multiple uses. The present investigation was carried out to evaluate the CNS depressant activity of methanolic fruit pulp extract of N. fruticans (MNF) on Swiss albino mice model by following the standard protocol of the hole cross test at three different dosages (200, 400 and 600 mg/kg body weight) against the standard diazepam. Here, MNF extract showed maximum suppression of motor activity (only 3.40 ± 0.49 number of movements) at 600 mg / kg after 120 minutes (p< 0.05). Therefore, the current study's findings indicate potent and dose-dependent CNS depressing action of MNF extract which can be used as a new source for the development of novel sedative-hypnotic drug. However, further investigation is required to find out the responsible phytoconstituents for the CNS depressant activity of MNF. Tasmim Farhana Anika B. Pharmacy 2024-07-15T05:14:49Z 2024-07-15T05:14:49Z ©2024 2024-02 Thesis ID 20146019 http://hdl.handle.net/10361/23696 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 66 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Nypa fruticans Wurmb Nipa palm CNS depressant Diazepam Hole cross test Medicinal plants Herbs--Therapeutic use |
| spellingShingle |
Nypa fruticans Wurmb Nipa palm CNS depressant Diazepam Hole cross test Medicinal plants Herbs--Therapeutic use Anika, Tasmim Farhana Assessment of CNS depressant activity of Nypa Fruticans Wurmb fruit pulp |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024. |
| author2 |
Ripa, Farhana Alam |
| author_facet |
Ripa, Farhana Alam Anika, Tasmim Farhana |
| format |
Thesis |
| author |
Anika, Tasmim Farhana |
| author_sort |
Anika, Tasmim Farhana |
| title |
Assessment of CNS depressant activity of Nypa Fruticans Wurmb fruit pulp |
| title_short |
Assessment of CNS depressant activity of Nypa Fruticans Wurmb fruit pulp |
| title_full |
Assessment of CNS depressant activity of Nypa Fruticans Wurmb fruit pulp |
| title_fullStr |
Assessment of CNS depressant activity of Nypa Fruticans Wurmb fruit pulp |
| title_full_unstemmed |
Assessment of CNS depressant activity of Nypa Fruticans Wurmb fruit pulp |
| title_sort |
assessment of cns depressant activity of nypa fruticans wurmb fruit pulp |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/23696 |
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AT anikatasmimfarhana assessmentofcnsdepressantactivityofnypafruticanswurmbfruitpulp |
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1814309000092581888 |