Effect Of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: A review
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2024
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| オンライン･アクセス: | http://hdl.handle.net/10361/23555 |
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10361-235552024-06-25T21:00:46Z Effect Of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: A review Mahin, Md. Tamjidur Rahman Kabir, Dr. Eva Rahman School of Pharmacy, BRAC University SGLT-2 inhibitors Obese Overweight Weight reduction Anti-obesity drugs Nondiabetic Glucose. Obesity--metabolism. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from the PDF version of the thesis. Includes bibliographical references (pages 24-25). Obesity is a global health concern and a large percentage of world is affected by it. Lifestyle changes are necessary and several therapy options are available to address it. Sodium glucose cotransporter 2 (SGLT-2) inhibitors show promising results in weight reduction. Although SGLT-2 inhibitors are approved by FDA for treating type 2 diabetes, recent trials have shown their effectiveness in weight loss. In the current study, the co-administration of 300 mg Canagliflozin and 15 mg phentermine has been found to have the highest efficacy, followed by 150 mg Licogliflozin once a day (q.d) and 25 mg Licogliflozin twice a day (b.i.d) which is moderately effective, and lastly 100 mg Canagliflozin once daily (q.d), which is has the lowest efficacy. Based on adverse effects like genital mycotic infection and urinary tract infections, Canagliflozin can be considered as a safe drug. Further clinical trials and post marketing data are required to confirm this finding. Md. Tamjidur Rahman Mahin B. Pharmacy 2024-06-25T03:33:24Z 2024-06-25T03:33:24Z 2022 2022-10 Thesis ID: 18346051 http://hdl.handle.net/10361/23555 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 25 pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
English |
| topic |
SGLT-2 inhibitors Obese Overweight Weight reduction Anti-obesity drugs Nondiabetic Glucose. Obesity--metabolism. |
| spellingShingle |
SGLT-2 inhibitors Obese Overweight Weight reduction Anti-obesity drugs Nondiabetic Glucose. Obesity--metabolism. Mahin, Md. Tamjidur Rahman Effect Of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: A review |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Kabir, Dr. Eva Rahman |
| author_facet |
Kabir, Dr. Eva Rahman Mahin, Md. Tamjidur Rahman |
| format |
Thesis |
| author |
Mahin, Md. Tamjidur Rahman |
| author_sort |
Mahin, Md. Tamjidur Rahman |
| title |
Effect Of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: A review |
| title_short |
Effect Of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: A review |
| title_full |
Effect Of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: A review |
| title_fullStr |
Effect Of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: A review |
| title_full_unstemmed |
Effect Of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: A review |
| title_sort |
effect of sodium glucose co-transporter 2 inhibitors on weight reduction in overweight and obese population: a review |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/23555 |
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AT mahinmdtamjidurrahman effectofsodiumglucosecotransporter2inhibitorsonweightreductioninoverweightandobesepopulationareview |
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