RNA drugs and RNA targets for small molecules: Prospects and challenges

This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.

Detalhes bibliográficos
Autor principal: Islam, Md. Raihanul
Outros Autores: Syed, Easin Uddin
Formato: Thesis
Idioma:English
Publicado em: Brac University 2024
Assuntos:
Acesso em linha:http://hdl.handle.net/10361/23553
id 10361-23553
record_format dspace
spelling 10361-235532024-06-25T21:01:07Z RNA drugs and RNA targets for small molecules: Prospects and challenges Islam, Md. Raihanul Syed, Easin Uddin School of Pharmacy, BRAC University RNA drugs RNA small molecules Gene slicing and editing RNase RNA molecule and Protein RNA therapeutics RNA-based therapy RNA editing. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. Cataloged from the PDF version of the thesis. Includes bibliographical references (pages 45-61). RNAs are the small molecules that have been inferred in many human diseases and they are important for gene regulation, gene expression, and cellular information transfer. The highly structured elements of the messenger RNA and non-coding RNAs are essential for the functions of the drugs. The small molecules combined with these RNAs provide a possibility to modulate diverse cellular processes therapeutically which incorporate them, who are linked to undruggable protein targets. However, only the linezolid antibiotics are clinically used among all other human-designed small molecules which target the RNA. With the identification of a huge number of small-molecule RNA ligands, the interest in this discipline is expanding. The purpose of this review is to explore the recent advancement with RNA drugs & target RNAs and the challenges for discovering suitable target structures and selective small molecule binders. Md. Raihanul Islam B. Pharmacy 2024-06-25T03:29:57Z 2024-06-25T03:29:57Z 2021 2021-08 Thesis ID: 15346033 http://hdl.handle.net/10361/23553 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 61 pages application/pdf Brac University
institution Brac University
collection Institutional Repository
language English
topic RNA drugs
RNA small molecules
Gene slicing and editing
RNase
RNA molecule and Protein
RNA therapeutics
RNA-based therapy
RNA editing.
spellingShingle RNA drugs
RNA small molecules
Gene slicing and editing
RNase
RNA molecule and Protein
RNA therapeutics
RNA-based therapy
RNA editing.
Islam, Md. Raihanul
RNA drugs and RNA targets for small molecules: Prospects and challenges
description This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.
author2 Syed, Easin Uddin
author_facet Syed, Easin Uddin
Islam, Md. Raihanul
format Thesis
author Islam, Md. Raihanul
author_sort Islam, Md. Raihanul
title RNA drugs and RNA targets for small molecules: Prospects and challenges
title_short RNA drugs and RNA targets for small molecules: Prospects and challenges
title_full RNA drugs and RNA targets for small molecules: Prospects and challenges
title_fullStr RNA drugs and RNA targets for small molecules: Prospects and challenges
title_full_unstemmed RNA drugs and RNA targets for small molecules: Prospects and challenges
title_sort rna drugs and rna targets for small molecules: prospects and challenges
publisher Brac University
publishDate 2024
url http://hdl.handle.net/10361/23553
work_keys_str_mv AT islammdraihanul rnadrugsandrnatargetsforsmallmoleculesprospectsandchallenges
_version_ 1814307224375263232