Review on simultaneous estimation of fixed dose combinations (FDC): system suitability testing (SST) parameters of RP-HPLC analysis
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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| التنسيق: | أطروحة |
| اللغة: | English |
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Brac University
2024
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://hdl.handle.net/10361/23248 |
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10361-23248 |
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10361-232482024-06-09T21:01:58Z Review on simultaneous estimation of fixed dose combinations (FDC): system suitability testing (SST) parameters of RP-HPLC analysis Khan, Masuma Karim, Eshaba School of Pharmacy, Brac University RP-HPLC RSD Theoretical plate number USP System suitability High performance liquid chromatography This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from the PDF version of thesis. Includes bibliographical references (pages 23-24). This study presents the system suitability criteria for the assessment of multiple fixed dose combinations using reversed - phase chromatography. RP-HPLC is a separation technique based on the lipophilic interaction between the solute molecules in the mobile phase and the aromatic ligand. System suitability tests are utilized to confirm that a chromatographic system is suitable for independent analysis. The assay of combinational oral dosage forms using RP-HPLC was studied in this review. The objective was to determine the compliance of the assays in existing literature meets SST characteristics established by the USP recommendation. If the characteristics were not met, the cause was identified and a possible solution was proposed. Twelve articles were identified as part of this research. Reviewing the system suitability testing (SST) parameters as per USP guideline suggested, reflects any potential lack of knowledge part in of method development in developing robust methods. Masuma Khan B. Pharmacy 2024-06-09T05:29:19Z 2024-06-09T05:29:19Z ©2022 2022-12 Thesis ID: 18346054 http://hdl.handle.net/10361/23248 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 40 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
RP-HPLC RSD Theoretical plate number USP System suitability High performance liquid chromatography |
| spellingShingle |
RP-HPLC RSD Theoretical plate number USP System suitability High performance liquid chromatography Khan, Masuma Review on simultaneous estimation of fixed dose combinations (FDC): system suitability testing (SST) parameters of RP-HPLC analysis |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Karim, Eshaba |
| author_facet |
Karim, Eshaba Khan, Masuma |
| format |
Thesis |
| author |
Khan, Masuma |
| author_sort |
Khan, Masuma |
| title |
Review on simultaneous estimation of fixed dose combinations (FDC): system suitability testing (SST) parameters of RP-HPLC analysis |
| title_short |
Review on simultaneous estimation of fixed dose combinations (FDC): system suitability testing (SST) parameters of RP-HPLC analysis |
| title_full |
Review on simultaneous estimation of fixed dose combinations (FDC): system suitability testing (SST) parameters of RP-HPLC analysis |
| title_fullStr |
Review on simultaneous estimation of fixed dose combinations (FDC): system suitability testing (SST) parameters of RP-HPLC analysis |
| title_full_unstemmed |
Review on simultaneous estimation of fixed dose combinations (FDC): system suitability testing (SST) parameters of RP-HPLC analysis |
| title_sort |
review on simultaneous estimation of fixed dose combinations (fdc): system suitability testing (sst) parameters of rp-hplc analysis |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/23248 |
| work_keys_str_mv |
AT khanmasuma reviewonsimultaneousestimationoffixeddosecombinationsfdcsystemsuitabilitytestingsstparametersofrphplcanalysis |
| _version_ |
1814307892984020992 |