An in-silico based multi epitope vaccine construction of flagellin protein opposing Helicobacter Pylori bacteria (H. Pylori)
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.
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| বিন্যাস: | গবেষণাপত্র |
| ভাষা: | English |
| প্রকাশিত: |
Brac University
2024
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | http://hdl.handle.net/10361/23236 |
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10361-23236 |
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10361-232362024-06-09T21:00:32Z An in-silico based multi epitope vaccine construction of flagellin protein opposing Helicobacter Pylori bacteria (H. Pylori) Akhter, Tahamina Siam, Mohammad Kawsar Sharif School of Pharmacy, Brac University FlaA protein H. pylori Multi-epitope vaccine In-silico CTL HTL Helicobacter pylori bacteria Vaccines Pathogenic bacteria This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024. Cataloged from the PDF version of thesis. Includes bibliographical references (pages 44-51). Helicobacter pylori (H. pylori) bacteria is a gram-negative bacteria that has capability to cause serious disease in human stomach by leading into peptic ulcer, mucosal lymph tissue, stomach cancer. According to WHO, it became type I carcinogen bacteria which colonizes and affects gastric mucosa layer of the stomach. Available antibiotics drugs were effective but now-days growing resistance to this particular bacterium. Hence, for such emerging situation a vaccine will be much more effective against bacterium; more convenient and budget friendly option to sufferer. In this study, protein sequence is used with different epitopes of Helper T cells, cytotoxic T cells, B cells to predict multi epitope-based vaccine for protection by computational (immunoinformatics) method. Tahamina Akhter B. Pharmacy 2024-06-09T04:36:57Z 2024-06-09T04:36:57Z ©2024 2024-02 Thesis ID: 19346005 http://hdl.handle.net/10361/23236 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 64 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
FlaA protein H. pylori Multi-epitope vaccine In-silico CTL HTL Helicobacter pylori bacteria Vaccines Pathogenic bacteria |
| spellingShingle |
FlaA protein H. pylori Multi-epitope vaccine In-silico CTL HTL Helicobacter pylori bacteria Vaccines Pathogenic bacteria Akhter, Tahamina An in-silico based multi epitope vaccine construction of flagellin protein opposing Helicobacter Pylori bacteria (H. Pylori) |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024. |
| author2 |
Siam, Mohammad Kawsar Sharif |
| author_facet |
Siam, Mohammad Kawsar Sharif Akhter, Tahamina |
| format |
Thesis |
| author |
Akhter, Tahamina |
| author_sort |
Akhter, Tahamina |
| title |
An in-silico based multi epitope vaccine construction of flagellin protein opposing Helicobacter Pylori bacteria (H. Pylori) |
| title_short |
An in-silico based multi epitope vaccine construction of flagellin protein opposing Helicobacter Pylori bacteria (H. Pylori) |
| title_full |
An in-silico based multi epitope vaccine construction of flagellin protein opposing Helicobacter Pylori bacteria (H. Pylori) |
| title_fullStr |
An in-silico based multi epitope vaccine construction of flagellin protein opposing Helicobacter Pylori bacteria (H. Pylori) |
| title_full_unstemmed |
An in-silico based multi epitope vaccine construction of flagellin protein opposing Helicobacter Pylori bacteria (H. Pylori) |
| title_sort |
in-silico based multi epitope vaccine construction of flagellin protein opposing helicobacter pylori bacteria (h. pylori) |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/23236 |
| work_keys_str_mv |
AT akhtertahamina aninsilicobasedmultiepitopevaccineconstructionofflagellinproteinopposinghelicobacterpyloribacteriahpylori AT akhtertahamina insilicobasedmultiepitopevaccineconstructionofflagellinproteinopposinghelicobacterpyloribacteriahpylori |
| _version_ |
1814306950732578816 |