Antimicrobial peptides in the treatment of dermatosis
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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| Lingua: | English |
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Brac University
2024
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| Accesso online: | http://hdl.handle.net/10361/23217 |
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10361-23217 |
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10361-232172024-06-06T21:01:12Z Antimicrobial peptides in the treatment of dermatosis Hussain, Sumaya Binty Rahman, Kazi Fatema School of Pharmacy, Brac University Atopic dermatitis Skin tissue infection Non-healing wound Cathelicidin-DM Dermatosis Skin disease Atopic dermatitis--Treatment Skin--Diseases--Treatment Peptide antibiotics This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from the PDF version of thesis. Includes bibliographical references (pages 29-32). Dermatosis refers to any skin defect or lesion on the skin due to scratches, wounds, ulcer, sunburn, skin abnormalities, skin thinning, different extrinsic and intrinsic factors and results allergy, skin infection, auto-immune disorder. For that skin protection decreases and it leads to damages of protective barrier and defensive system. Several conventional medication including antibiotics is using for dermatosis. But with uprising antibiotic resistance, the use of these antibiotics is compromised. The discovery or the design of antimicrobials with lower susceptibility to antimicrobial resistance is a key for the effective treatment of bacterial infections. Antimicrobial peptides appear to be promising therapeutic options for the treatment of dermatosis including soft skin tissue infections, atopic dermatitis and critical non-healing wound. Many peptides have broad spectrum antimicrobial activity against bacteria, fungi, and viruses. This comprehensive review highlights different skin diseases and conventional treatment complications, source of antimicrobial peptides and their potential activity against dermatosis causing microorganisms. Patients with diabetic mellitus are prone to have diabetic foot infection and critical non-healing wound. Some peptides work great to improve those condition. Also, Cathelicidin-DM can improve infected non-healing wound. Though, there are some limitations and challenges in AMPs development process for therapeutic purpose. But with more research on limitation, better understanding about AMPs, structural modification of AMPs can lead to develop a smart, safe and effective treatment. Sumaya Binty Hussain B. Pharmacy 2024-06-06T09:34:34Z 2024-06-06T09:34:34Z ©2023 2023-02 Thesis ID: 19146054 http://hdl.handle.net/10361/23217 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 44 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Atopic dermatitis Skin tissue infection Non-healing wound Cathelicidin-DM Dermatosis Skin disease Atopic dermatitis--Treatment Skin--Diseases--Treatment Peptide antibiotics |
| spellingShingle |
Atopic dermatitis Skin tissue infection Non-healing wound Cathelicidin-DM Dermatosis Skin disease Atopic dermatitis--Treatment Skin--Diseases--Treatment Peptide antibiotics Hussain, Sumaya Binty Antimicrobial peptides in the treatment of dermatosis |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Rahman, Kazi Fatema |
| author_facet |
Rahman, Kazi Fatema Hussain, Sumaya Binty |
| format |
Thesis |
| author |
Hussain, Sumaya Binty |
| author_sort |
Hussain, Sumaya Binty |
| title |
Antimicrobial peptides in the treatment of dermatosis |
| title_short |
Antimicrobial peptides in the treatment of dermatosis |
| title_full |
Antimicrobial peptides in the treatment of dermatosis |
| title_fullStr |
Antimicrobial peptides in the treatment of dermatosis |
| title_full_unstemmed |
Antimicrobial peptides in the treatment of dermatosis |
| title_sort |
antimicrobial peptides in the treatment of dermatosis |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/23217 |
| work_keys_str_mv |
AT hussainsumayabinty antimicrobialpeptidesinthetreatmentofdermatosis |
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1814307374379302912 |