A review of Isotretinoin and its association in affective disorder

This project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.

Bibliographic Details
Main Author: Sarkar, Argha
Other Authors: Islam, Farzana
Format: Project report
Language:English
Published: Brac University 2024
Subjects:
Online Access:http://hdl.handle.net/10361/23195
id 10361-23195
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spelling 10361-231952024-06-06T21:02:49Z A review of Isotretinoin and its association in affective disorder Sarkar, Argha Islam, Farzana School of Pharmacy, Brac University Isotretinoin Retinoic acid Vitamin A Mental health Depression Isotretinoin--Side effects Retinoids--Therapeutic use This project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from the PDF version of project report. Includes bibliographical references (pages 26-28). Isotretinoin is a medication used in the treatment of severe to moderate acne. However, several studies have reported a potential association between Isotretinoin use and affective disorders (depression, anxiety, suicidal ideation). In the review, an attempt is made to understand how the use of Isotretinoin is associated with affective disorder. Several published materials reporting psychiatric side effects following Isotretinoin treatment including case reports were being studied for this review. Some studies have proposed a possible connection between Isotretinoin usage and affective disorders where retinoic acid plays a crucial role. Retinoic acid may cross the blood-brain barrier so it can have an effect on CNS which may lead to affective disorder. However, no causal relationship has not been established and the link between Isotretinoin use and psychiatric events remains controversial. Because of the lack of evidence, broad research is needed to understand the relationship between Isotretinoin and mental health outcomes. Argha Sarkar B. Pharmacy 2024-06-06T05:41:19Z 2024-06-06T05:41:19Z ©2023 2023-03 Project report ID: 19146077 http://hdl.handle.net/10361/23195 en Brac University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 40 pages application/pdf Brac University
institution Brac University
collection Institutional Repository
language English
topic Isotretinoin
Retinoic acid
Vitamin A
Mental health
Depression
Isotretinoin--Side effects
Retinoids--Therapeutic use
spellingShingle Isotretinoin
Retinoic acid
Vitamin A
Mental health
Depression
Isotretinoin--Side effects
Retinoids--Therapeutic use
Sarkar, Argha
A review of Isotretinoin and its association in affective disorder
description This project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
author2 Islam, Farzana
author_facet Islam, Farzana
Sarkar, Argha
format Project report
author Sarkar, Argha
author_sort Sarkar, Argha
title A review of Isotretinoin and its association in affective disorder
title_short A review of Isotretinoin and its association in affective disorder
title_full A review of Isotretinoin and its association in affective disorder
title_fullStr A review of Isotretinoin and its association in affective disorder
title_full_unstemmed A review of Isotretinoin and its association in affective disorder
title_sort review of isotretinoin and its association in affective disorder
publisher Brac University
publishDate 2024
url http://hdl.handle.net/10361/23195
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