A review on the association of SNP at rs731236 of VDR Gene and different diseases in various ethnicity
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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| Lingua: | English |
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Brac University
2024
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| Accesso online: | http://hdl.handle.net/10361/23131 |
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10361-23131 |
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10361-231312024-06-06T08:07:06Z A review on the association of SNP at rs731236 of VDR Gene and different diseases in various ethnicity Rafique, Usrat Rifat Binte Haque, Md. Aminul School of Pharmacy, Brac University Vitamin D Polymorphism VDR gene Autoimmune disease SNP association Genetic polymorphism Rheumatoid arthritis Single nucleotide polymorphisms This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from the PDF version of thesis. Includes bibliographical references (pages 24-28). There is much of information on vitamin D's importance in bone metabolism, but less is known about how it affects other organs or systems. Vitamin D is receptor is found in the kidney, pancreas, prostate, gut, platelets, and immune cells where it is synthesizing 1- hydroxylase enzyme showing that it is actively connected in these cell populations and disorders related to them. Diseases like rheumatoid arthritis, Behcets diseases, osteoporosis, allergic disease and renal dysfunction. The frequency of genotype and alleles of various VDR polymorphism with such disorders in Egyptian, Tunisian, Caucasian, Asian, German, Spanish and some other European population has proved to be connected. The only suggested treatment to maintain the homeostasis of Vitamin-d to regulate normal VDR activity is vitamin D supplementation though more research work should be done focusing VDR polymorphism related diseases and their treatment. Usrat Rifat Binte Rafique B. Pharmacy 2024-06-05T03:40:32Z 2024-06-05T03:40:32Z ©2023 2023-02 Thesis ID: 19146063 http://hdl.handle.net/10361/23131 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 46 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Vitamin D Polymorphism VDR gene Autoimmune disease SNP association Genetic polymorphism Rheumatoid arthritis Single nucleotide polymorphisms |
| spellingShingle |
Vitamin D Polymorphism VDR gene Autoimmune disease SNP association Genetic polymorphism Rheumatoid arthritis Single nucleotide polymorphisms Rafique, Usrat Rifat Binte A review on the association of SNP at rs731236 of VDR Gene and different diseases in various ethnicity |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Haque, Md. Aminul |
| author_facet |
Haque, Md. Aminul Rafique, Usrat Rifat Binte |
| format |
Thesis |
| author |
Rafique, Usrat Rifat Binte |
| author_sort |
Rafique, Usrat Rifat Binte |
| title |
A review on the association of SNP at rs731236 of VDR Gene and different diseases in various ethnicity |
| title_short |
A review on the association of SNP at rs731236 of VDR Gene and different diseases in various ethnicity |
| title_full |
A review on the association of SNP at rs731236 of VDR Gene and different diseases in various ethnicity |
| title_fullStr |
A review on the association of SNP at rs731236 of VDR Gene and different diseases in various ethnicity |
| title_full_unstemmed |
A review on the association of SNP at rs731236 of VDR Gene and different diseases in various ethnicity |
| title_sort |
review on the association of snp at rs731236 of vdr gene and different diseases in various ethnicity |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/23131 |
| work_keys_str_mv |
AT rafiqueusratrifatbinte areviewontheassociationofsnpatrs731236ofvdrgeneanddifferentdiseasesinvariousethnicity AT rafiqueusratrifatbinte reviewontheassociationofsnpatrs731236ofvdrgeneanddifferentdiseasesinvariousethnicity |
| _version_ |
1814309234786959360 |