Efficacy of sertraline in the treatment of major depressive disorder smong adult population: a systematic review
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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Brac University
2024
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10361-231282024-06-04T21:01:48Z Efficacy of sertraline in the treatment of major depressive disorder smong adult population: a systematic review Maha, Tasfiah Tasnim Kabir, Eva Rahman School of Pharmacy, Brac University Sertraline Efficacy Major depressive disorder Antidepressant Risk of bias Mental illness. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from the PDF version of thesis. Includes bibliographical references (pages 29-35). With an increasing prevalence of Major Depressive Disorder (MDD) throughout the past few years, it has been crucial to examine the effectiveness of antidepressants in order to treat and manage such conditions. Due to the complex heterogenicity in terms of the pathophysiology of such psychiatric disorders, assessing the clinical effectiveness of available pharmacological interventions is of concern. The aim of the systematic review is to investigate the efficacy of an FDA approved antidepressant, Sertraline in the treatment of MDD in adult population. A literature search of Randomized Control Trials (RCTs) was performed in PubMed based on a prespecification of eligibility criteria in order to extract studies evaluating and comparing the efficacy of Sertraline in patients with clinically diagnosed MDD either with another antidepressant or placebo. Risk of bias as well as methodological qualities of each individual study was also assessed in order to address the qualities of studies incorporated. Tasfiah Tasnim Maha B. Pharmacy 2024-06-04T10:42:22Z 2024-06-04T10:42:22Z 2023 2023-08 Thesis ID 19346010 http://hdl.handle.net/10361/23128 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 35 pages application/pdf Brac University |
institution |
Brac University |
collection |
Institutional Repository |
language |
English |
topic |
Sertraline Efficacy Major depressive disorder Antidepressant Risk of bias Mental illness. |
spellingShingle |
Sertraline Efficacy Major depressive disorder Antidepressant Risk of bias Mental illness. Maha, Tasfiah Tasnim Efficacy of sertraline in the treatment of major depressive disorder smong adult population: a systematic review |
description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
author2 |
Kabir, Eva Rahman |
author_facet |
Kabir, Eva Rahman Maha, Tasfiah Tasnim |
format |
Thesis |
author |
Maha, Tasfiah Tasnim |
author_sort |
Maha, Tasfiah Tasnim |
title |
Efficacy of sertraline in the treatment of major depressive disorder smong adult population: a systematic review |
title_short |
Efficacy of sertraline in the treatment of major depressive disorder smong adult population: a systematic review |
title_full |
Efficacy of sertraline in the treatment of major depressive disorder smong adult population: a systematic review |
title_fullStr |
Efficacy of sertraline in the treatment of major depressive disorder smong adult population: a systematic review |
title_full_unstemmed |
Efficacy of sertraline in the treatment of major depressive disorder smong adult population: a systematic review |
title_sort |
efficacy of sertraline in the treatment of major depressive disorder smong adult population: a systematic review |
publisher |
Brac University |
publishDate |
2024 |
url |
http://hdl.handle.net/10361/23128 |
work_keys_str_mv |
AT mahatasfiahtasnim efficacyofsertralineinthetreatmentofmajordepressivedisordersmongadultpopulationasystematicreview |
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