Synthesis and sar o acne medication
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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| स्वरूप: | थीसिस |
| भाषा: | English |
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Brac University
2024
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| ऑनलाइन पहुंच: | http://hdl.handle.net/10361/22887 |
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10361-22887 |
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10361-228872024-05-20T21:01:08Z Synthesis and sar o acne medication Naureen, Tasnia Omer, Humair Bin Md School of Pharmacy, Brac University Acne vulgaris Synthesis Androgen SAR Inhibitors Acne Androgens--Pathophysiology This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from PDF version of thesis. Includes bibliographical references (pages 34-36). This undergraduate research thesis explores the synthesis and structure-activity relationships (SAR) of drugs used for the treatment of acne vulgaris, which affects approximately 85% of individuals between the ages of 12 and 25. The objective of this review is to investigate the etiology of acne, current therapies, drugs used for treatment, their SAR, and synthesis. The pathophysiology of acne is multifactorial and includes increased sebum production, aberrant follicular keratinization, an increase in Propionibacterium acnes, and inflammation. The methodology used for this study involved searching for relevant articles on Google Scholar, PubMed, and Web of Science. Additionally, the study delves into the enzyme 5α-reductase, which may be the root cause of androgen production and consequently the development of acne. The review article indicates that an excess of precursor androgens, particularly in individuals with severe acne, can lead to hormonal imbalances and the development of the condition. The synthesis of newer acne medications and further research in this field will provide a better understanding of the varying degrees of effectiveness of acne medication from person to person. Tasnia Naureen B. Pharmacy 2024-05-20T06:47:23Z 2024-05-20T06:47:23Z © 2023 2023-02 Thesis ID 19146043 http://hdl.handle.net/10361/22887 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 46 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Acne vulgaris Synthesis Androgen SAR Inhibitors Acne Androgens--Pathophysiology |
| spellingShingle |
Acne vulgaris Synthesis Androgen SAR Inhibitors Acne Androgens--Pathophysiology Naureen, Tasnia Synthesis and sar o acne medication |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Omer, Humair Bin Md |
| author_facet |
Omer, Humair Bin Md Naureen, Tasnia |
| format |
Thesis |
| author |
Naureen, Tasnia |
| author_sort |
Naureen, Tasnia |
| title |
Synthesis and sar o acne medication |
| title_short |
Synthesis and sar o acne medication |
| title_full |
Synthesis and sar o acne medication |
| title_fullStr |
Synthesis and sar o acne medication |
| title_full_unstemmed |
Synthesis and sar o acne medication |
| title_sort |
synthesis and sar o acne medication |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/22887 |
| work_keys_str_mv |
AT naureentasnia synthesisandsaroacnemedication |
| _version_ |
1814307441833148416 |