Evaluation of the safety and efficacy of oral isotretinoin in the treatment of acne
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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Brac University
2024
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| 在线阅读: | http://hdl.handle.net/10361/22847 |
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10361-228472024-05-16T21:01:57Z Evaluation of the safety and efficacy of oral isotretinoin in the treatment of acne Bose, Ankita Islam, Farzana School of Pharmacy, Brac University Acne Retinoid Isotretinoin Teratogenicity Acne--Treatment Isotretinoin--Side effects Retinoids--Health aspects This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from PDF version of thesis. Includes bibliographical references (pages 26-39). Acne is a prevalent skin disorder. Isotretinoin is an FDA-approved retinoic acid isomer frequently used to cure or remission this obstinate condition when other procurable approaches and antibiotics fail. However, the oral form is reportedly responsible for some unusual side effects in some patients. This systematic review is intended to summarize the findings regarding safety, efficacy and any observed side effects throughout the oral Isotretinoin treatment. Data about acne pathogenesis, epidemiology and mechanism of action of Isotretinoin was also synthesized. According to the tabular representation of information, it can be considered that incident of side effects and adverse drug reaction occurrence is typically dose-dependent and sometimes reversible with some specific precautions. Severe adverse incidents such as teratogenicity are quite uncommon and can be avoided by adhering to safety regulations or using contraception. However, considering the negligible occurrence of adverse events and adequate patient satisfaction, isotretinoin can be an economical and efficient choice for the First-line treatment for acne treatment and reduce the use of oral or topical antibiotics in this antibiotic resistance awareness era. B. Pharmacy 2024-05-16T04:22:37Z 2024-05-16T04:22:37Z © 2023 2023-10 Thesis ID 19146010 http://hdl.handle.net/10361/22847 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 56 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Acne Retinoid Isotretinoin Teratogenicity Acne--Treatment Isotretinoin--Side effects Retinoids--Health aspects |
| spellingShingle |
Acne Retinoid Isotretinoin Teratogenicity Acne--Treatment Isotretinoin--Side effects Retinoids--Health aspects Bose, Ankita Evaluation of the safety and efficacy of oral isotretinoin in the treatment of acne |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Islam, Farzana |
| author_facet |
Islam, Farzana Bose, Ankita |
| format |
Thesis |
| author |
Bose, Ankita |
| author_sort |
Bose, Ankita |
| title |
Evaluation of the safety and efficacy of oral isotretinoin in the treatment of acne |
| title_short |
Evaluation of the safety and efficacy of oral isotretinoin in the treatment of acne |
| title_full |
Evaluation of the safety and efficacy of oral isotretinoin in the treatment of acne |
| title_fullStr |
Evaluation of the safety and efficacy of oral isotretinoin in the treatment of acne |
| title_full_unstemmed |
Evaluation of the safety and efficacy of oral isotretinoin in the treatment of acne |
| title_sort |
evaluation of the safety and efficacy of oral isotretinoin in the treatment of acne |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/22847 |
| work_keys_str_mv |
AT boseankita evaluationofthesafetyandefficacyoforalisotretinoininthetreatmentofacne |
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1814308094122917888 |