Evaluation of anti-diarrheal activity of methanolic flesh extract of Flacourtia jangomas on mice
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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Brac University
2024
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| Online Erişim: | http://hdl.handle.net/10361/22255 |
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10361-222552024-01-30T21:02:39Z Evaluation of anti-diarrheal activity of methanolic flesh extract of Flacourtia jangomas on mice Susmita, Nusrat Jahan Ripa, Farhana Alam Chowdhury, Namara Mariam School of Pharmacy, Brac University Flacourtia. jangomas Anti-diarrheal activity Castor oil Methanol Swiss albino mice Diarrhea--Treatment This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from PDF version of thesis. Includes bibliographical references (pages 34-36). "Flacourtia jangomas is rare fruit, rarely found in hill tracks of Bangladesh. This is a less researched fruits but have many phytochemical constituent. It contain many pharmacological activity as well. The fact that F. jangomas is now thought to be an excellent reservoir of chemicals such phenol, tannin, alkaloids, flavanoids, and terpenoids that may be a better source to cure diarrhea is a major driving force behind this research. This study tested the F. jangomas flesh in vivo antidiarrheal effect on Swiss albino mice. In order to compare the test results, Loperamide was utilized as the reference medication. Three concentrations of F. jangomas (15mg/ml, 30mg/ml and 45mg/ml) of each extract showed antidiarrheal activity. The results have been elucidated as number of feces in every 1hr. The number feces counted till 4hrs. The antidiarrheal activity of methanolic flesh per hour until 4hrs extract of F.jangomas at 100,200and 300mg/kg concentration showed number of feces time respectively is 10.83, 9.67 and 8.65 in 4hrs. F. jangoma showed the effectiveness of antidiarrheal activity 14.52%, 23.68%and 32.91% respectively. All the result were significant (P<0.001) for the antidiarrheal activity. This study highlights the significance of F. jangomasin's use as an antidiarrheal agent and the need for additional research to identify the active ingredient that causes this effect." Nusrat Jahan Susmita B. Pharmacy 2024-01-30T06:15:36Z 2024-01-30T06:15:36Z 2023 2022-11 Thesis ID 18346046 http://hdl.handle.net/10361/22255 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 48 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Flacourtia. jangomas Anti-diarrheal activity Castor oil Methanol Swiss albino mice Diarrhea--Treatment |
| spellingShingle |
Flacourtia. jangomas Anti-diarrheal activity Castor oil Methanol Swiss albino mice Diarrhea--Treatment Susmita, Nusrat Jahan Evaluation of anti-diarrheal activity of methanolic flesh extract of Flacourtia jangomas on mice |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Ripa, Farhana Alam |
| author_facet |
Ripa, Farhana Alam Susmita, Nusrat Jahan |
| format |
Thesis |
| author |
Susmita, Nusrat Jahan |
| author_sort |
Susmita, Nusrat Jahan |
| title |
Evaluation of anti-diarrheal activity of methanolic flesh extract of Flacourtia jangomas on mice |
| title_short |
Evaluation of anti-diarrheal activity of methanolic flesh extract of Flacourtia jangomas on mice |
| title_full |
Evaluation of anti-diarrheal activity of methanolic flesh extract of Flacourtia jangomas on mice |
| title_fullStr |
Evaluation of anti-diarrheal activity of methanolic flesh extract of Flacourtia jangomas on mice |
| title_full_unstemmed |
Evaluation of anti-diarrheal activity of methanolic flesh extract of Flacourtia jangomas on mice |
| title_sort |
evaluation of anti-diarrheal activity of methanolic flesh extract of flacourtia jangomas on mice |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/22255 |
| work_keys_str_mv |
AT susmitanusratjahan evaluationofantidiarrhealactivityofmethanolicfleshextractofflacourtiajangomasonmice |
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1814309591741104128 |