A review: combination of photon emission & genome engineering in brain stimulation
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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Brac University
2024
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| Rochtain ar líne: | http://hdl.handle.net/10361/22047 |
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10361-220472024-01-02T21:02:38Z A review: combination of photon emission & genome engineering in brain stimulation Audithi, Atiya Sunjida Haque, Md. Aminul School of Pharmacy, Brac University Optogenetics Brain stimulation Opsin Genome engineering Photon emission Light Photon emission Brain stimulation This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from PDF version of thesis. Includes bibliographical references (pages 31-36). Genome engineering and photon emission enables optogenetic brain stimulation. Neurological disorders and brain function research require brain stimulation. This review discusses optogenetics, a new technology that controls genetically defined neurons using light. Genetically engineered cells express light-sensitive opsin first. When engineered cells are illuminated, opsin-bound retinal conformationally shifts to open channels or pumps, depolarize or hyperpolarize cells, and activate or mute neurons. After the invention optogenetics, many opsin variants have been discovered or produced, allowing different wavelengths of light to activate or inhibit neural activity. Optogenetics has helped scientists comprehend brain circuit dysfunction that causes mental illness, stroke, heart disease, etc. Genome engineering and photon emission also enabled brain mapping. Optogenetics has transformed neuroscience and enabled new research to investigate casual roles of any particular brain circuit. Atiya Sunjida Audithi B. Pharmacy 2024-01-02T05:30:56Z 2024-01-02T05:30:56Z 2023 2023-02 Thesis ID 19146017 http://hdl.handle.net/10361/22047 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 36 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Optogenetics Brain stimulation Opsin Genome engineering Photon emission Light Photon emission Brain stimulation |
| spellingShingle |
Optogenetics Brain stimulation Opsin Genome engineering Photon emission Light Photon emission Brain stimulation Audithi, Atiya Sunjida A review: combination of photon emission & genome engineering in brain stimulation |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Haque, Md. Aminul |
| author_facet |
Haque, Md. Aminul Audithi, Atiya Sunjida |
| format |
Thesis |
| author |
Audithi, Atiya Sunjida |
| author_sort |
Audithi, Atiya Sunjida |
| title |
A review: combination of photon emission & genome engineering in brain stimulation |
| title_short |
A review: combination of photon emission & genome engineering in brain stimulation |
| title_full |
A review: combination of photon emission & genome engineering in brain stimulation |
| title_fullStr |
A review: combination of photon emission & genome engineering in brain stimulation |
| title_full_unstemmed |
A review: combination of photon emission & genome engineering in brain stimulation |
| title_sort |
review: combination of photon emission & genome engineering in brain stimulation |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/22047 |
| work_keys_str_mv |
AT audithiatiyasunjida areviewcombinationofphotonemissiongenomeengineeringinbrainstimulation AT audithiatiyasunjida reviewcombinationofphotonemissiongenomeengineeringinbrainstimulation |
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1814308091004452864 |