Relationship between SGLT2 inhibitor use and risk of lower limb amputations: a pharmacovigilance study
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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| বিন্যাস: | গবেষণাপত্র |
| ভাষা: | English |
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Brac University
2024
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| অনলাইন ব্যবহার করুন: | http://hdl.handle.net/10361/22046 |
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10361-220462024-01-02T21:02:35Z Relationship between SGLT2 inhibitor use and risk of lower limb amputations: a pharmacovigilance study Khandker, Tahia Anjum Kabir, Eva Rahman School of Pharmacy, Brac University SGLT2 inhibitors Canagliflozin Adverse events Type 2 diabetes mellitus Lower limb amputations FAERS Amputees--Rehabilitation Artificial limbs This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from PDF version of thesis. Includes bibliographical references (pages 32-39). Type 2 Diabetes Mellitus is a chronic, complicated, multifactorial condition affecting millions of people worldwide. A variety of anti-diabetic pharmacological interventions are available for the condition. Amongst many such drugs, SGLT2 inhibitors have multiple benefits such as reno-protection, weight loss, and reduced hypertension. However, some harmful adverse effects also exist that need to be addressed and monitored to ensure patient safety. For instance, these drugs are suspected to be linked to an increased risk of limb amputations, although findings from previous studies remain inconclusive. The current study therefore collected post- marketing data from the FAERS database to establish or disprove a significant association between use of SGLT2 inhibitors and increased risk of limb amputations. Tahia Anjum Khandker B. Pharmacy 2024-01-02T05:03:05Z 2024-01-02T05:03:05Z 2023 2023-03 Thesis ID 19146015 http://hdl.handle.net/10361/22046 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 39 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
SGLT2 inhibitors Canagliflozin Adverse events Type 2 diabetes mellitus Lower limb amputations FAERS Amputees--Rehabilitation Artificial limbs |
| spellingShingle |
SGLT2 inhibitors Canagliflozin Adverse events Type 2 diabetes mellitus Lower limb amputations FAERS Amputees--Rehabilitation Artificial limbs Khandker, Tahia Anjum Relationship between SGLT2 inhibitor use and risk of lower limb amputations: a pharmacovigilance study |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Kabir, Eva Rahman |
| author_facet |
Kabir, Eva Rahman Khandker, Tahia Anjum |
| format |
Thesis |
| author |
Khandker, Tahia Anjum |
| author_sort |
Khandker, Tahia Anjum |
| title |
Relationship between SGLT2 inhibitor use and risk of lower limb amputations: a pharmacovigilance study |
| title_short |
Relationship between SGLT2 inhibitor use and risk of lower limb amputations: a pharmacovigilance study |
| title_full |
Relationship between SGLT2 inhibitor use and risk of lower limb amputations: a pharmacovigilance study |
| title_fullStr |
Relationship between SGLT2 inhibitor use and risk of lower limb amputations: a pharmacovigilance study |
| title_full_unstemmed |
Relationship between SGLT2 inhibitor use and risk of lower limb amputations: a pharmacovigilance study |
| title_sort |
relationship between sglt2 inhibitor use and risk of lower limb amputations: a pharmacovigilance study |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/22046 |
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AT khandkertahiaanjum relationshipbetweensglt2inhibitoruseandriskoflowerlimbamputationsapharmacovigilancestudy |
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