An review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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| Lenguaje: | English |
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Brac University
2023
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| Acceso en línea: | http://hdl.handle.net/10361/22001 |
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10361-22001 |
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10361-220012023-12-18T21:02:36Z An review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis Bahar, Nazia Binta Omer, Humair Bin Md. School of Pharmacy, Brac University Anticancer drug Alkylating agents Mechanism of action Synthesis This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cancer is known as one of the world’s deadliest diseases characterized by uncontrolled cellular proliferation. Alkylating agents are one class of anticancer drugs which cross-link DNA strands and induce cell death. The ultimate objective of alkylating agents is to enhance patient outcomes and lessen the impact of cancer on society. In this review article, a thorough overview of alkylating agents utilized in cancer treatment is covered. It will discuss mechanism of actions, structure-activity relationships (SARs), synthesis, and potential future direction of alkylating agents. Specifically, alkylating agents that are historically important, currently used or seem promising in clinical trials are mainly discussed here. The objective of the review is expected to aid pharmacologists, synthetic and medicinal chemists and other healthcare professionals who are working in the field of antineoplastic drugs to provide a state-of-the-art knowledge in making these drugs, mechanisms of actions and its synthetic procedures in the literature. Nazia Binta Bahar B. Pharmacy 2023-12-18T06:03:54Z 2023-12-18T06:03:54Z 2023 2023-07 Thesis ID 19346021 http://hdl.handle.net/10361/22001 en application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Anticancer drug Alkylating agents Mechanism of action Synthesis |
| spellingShingle |
Anticancer drug Alkylating agents Mechanism of action Synthesis Bahar, Nazia Binta An review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Omer, Humair Bin Md. |
| author_facet |
Omer, Humair Bin Md. Bahar, Nazia Binta |
| format |
Thesis |
| author |
Bahar, Nazia Binta |
| author_sort |
Bahar, Nazia Binta |
| title |
An review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis |
| title_short |
An review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis |
| title_full |
An review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis |
| title_fullStr |
An review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis |
| title_full_unstemmed |
An review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis |
| title_sort |
review of alkylating-like agents in reducing mortality of cancer patients: structure & synthesis |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/22001 |
| work_keys_str_mv |
AT baharnaziabinta anreviewofalkylatinglikeagentsinreducingmortalityofcancerpatientsstructuresynthesis AT baharnaziabinta reviewofalkylatinglikeagentsinreducingmortalityofcancerpatientsstructuresynthesis |
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