Characterization of acinetobacter baumannii from hospital-adjacent waterbodies in Dhaka city
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2023.
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Brac University
2023
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| Διαθέσιμο Online: | http://hdl.handle.net/10361/21973 |
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10361-219732023-12-13T21:02:33Z Characterization of acinetobacter baumannii from hospital-adjacent waterbodies in Dhaka city Saiyan, Zwad Al Jahan, Afia Haque, Fahim Kabir Monjurul Department of Mathematics and Natural Sciences, Brac University Acinetobacterbaumannii Surface water Antibiotic resistance Multidrug resistance This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2023. Catalogued from PDF version of thesis. Includes bibliographical references (pages 22-26). Acinetobacter baumannii has become a significant pathogen over the last few decades. It is naturally found in food, soil, and surface water but in clinical settings, it has demonstrated increasing health problems and nosocomial infections with limited antibiotic treatment options. The presence of multidrug-resistantA. baumannii in hospital settings and from clinical samples have been well documented but their spread in the natural environment is still poorly understood. In this study, A. baumannii were isolated from four waterbodies adjacent (within a 100-200 meter range) to four different hospitals. The samples were collected consecutively for four months to observe the prevalence of the organism. Out of 16 samples 21 positive isolates were confirmed by PCR of the blaOXA51 gene. Subsequently, susceptibility test was carried out for 13 antibiotics from seven different antibiotic classes. The test reported that all isolates (95%) except for one (LM2) were resistant to Ceftazidime meanwhile, 95% of the isolates were susceptible to Meropenem and Gentamicin except for MMY4 and LA7 respectively. The resistance pattern for other antibiotics was as follows: Ceftriaxone (48%), Piperacillin (33%), Trimethoprim (28%), and Cefepime (28%). Notedly, 33.33% of the isolates were in the intermediate category for Ciprofloxacin and Piperacillin. Moreover, the MAR index of 7 out of the 21 isolates was higher than 0.28. indicating the sources of these isolates are exposed to antibiotics at a higher level. Finally, among the 21 isolates, 8 isolates (38%) were found to be resistant to three or more categories of antibiotics making them multidrug-resistant. Zwad Al Saiyan Afia Jahan B. Microbiology 2023-12-13T04:27:58Z 2023-12-13T04:27:58Z 2023 2023-06 Thesis ID 19126030 ID 18236011 http://hdl.handle.net/10361/21973 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 26 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Acinetobacterbaumannii Surface water Antibiotic resistance Multidrug resistance |
| spellingShingle |
Acinetobacterbaumannii Surface water Antibiotic resistance Multidrug resistance Saiyan, Zwad Al Jahan, Afia Characterization of acinetobacter baumannii from hospital-adjacent waterbodies in Dhaka city |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Microbiology, 2023. |
| author2 |
Haque, Fahim Kabir Monjurul |
| author_facet |
Haque, Fahim Kabir Monjurul Saiyan, Zwad Al Jahan, Afia |
| format |
Thesis |
| author |
Saiyan, Zwad Al Jahan, Afia |
| author_sort |
Saiyan, Zwad Al |
| title |
Characterization of acinetobacter baumannii from hospital-adjacent waterbodies in Dhaka city |
| title_short |
Characterization of acinetobacter baumannii from hospital-adjacent waterbodies in Dhaka city |
| title_full |
Characterization of acinetobacter baumannii from hospital-adjacent waterbodies in Dhaka city |
| title_fullStr |
Characterization of acinetobacter baumannii from hospital-adjacent waterbodies in Dhaka city |
| title_full_unstemmed |
Characterization of acinetobacter baumannii from hospital-adjacent waterbodies in Dhaka city |
| title_sort |
characterization of acinetobacter baumannii from hospital-adjacent waterbodies in dhaka city |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/21973 |
| work_keys_str_mv |
AT saiyanzwadal characterizationofacinetobacterbaumanniifromhospitaladjacentwaterbodiesindhakacity AT jahanafia characterizationofacinetobacterbaumanniifromhospitaladjacentwaterbodiesindhakacity |
| _version_ |
1814308569822003200 |