Demystifying lanthanomes: a pangenomic approach
This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2023.
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| Формат: | Диссертация |
| Язык: | English |
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Brac University
2023
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| Online-ссылка: | http://hdl.handle.net/10361/21408 |
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10361-214082023-10-01T21:02:58Z Demystifying lanthanomes: a pangenomic approach Rafsan, Rian Nasser, Iftekhar Bin Shishir, Tushar Ahmed Department of Mathematics and Natural Sciences, Brac University Lanthanomes Lanthanide metals Biotechnology This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2023. Cataloged from PDF version of thesis. Includes bibliographical references (pages 55-57). Certain members of multi-generic, gram negative proteobacteria (newly named pseudomonatota) have recently been reported to be capable of successfully utilizing the catalytic potential of lanthanide metals for the efficient dehydrogenation of alcohols as a part of their respective regular metabolism. While recent studies did essentially help the characterization of most genes responsible for such lanthanomic behavior, much of the knowledge space regarding lanthanomes is still engulfed in a void. With an aim to potentially reduce this knowledge gap we conducted an in silico pangenomic analysis on 31 non redundant strains spanning 23 genera, who were previously proven to be lanthanomes in a typical wet lab. We tried to confirm the lanthonomicity of these microorganisms by screening the resultant pangenome for lanthanide dependent genesxoxF, xoxG, ExaF, PedH, fldA & gfaA. The analysis resulted in 181 core, 292 soft core, 7894 shell & 26805 cloud gene clusters respectively, while 26 of the 31 strains showed the presence of at least 1 of the selected lanthanomic genes. The results also support the heterogenic and subsequently divergent behavior of lanthanomes alongside events of concurrent clustering & genetic duplication. Rian Rafsan M. Biotechnology 2023-10-01T07:00:16Z 2023-10-01T07:00:16Z 2023 2023-04 Thesis ID 21276004 http://hdl.handle.net/10361/21408 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 57 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Lanthanomes Lanthanide metals Biotechnology |
| spellingShingle |
Lanthanomes Lanthanide metals Biotechnology Rafsan, Rian Demystifying lanthanomes: a pangenomic approach |
| description |
This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2023. |
| author2 |
Nasser, Iftekhar Bin |
| author_facet |
Nasser, Iftekhar Bin Rafsan, Rian |
| format |
Thesis |
| author |
Rafsan, Rian |
| author_sort |
Rafsan, Rian |
| title |
Demystifying lanthanomes: a pangenomic approach |
| title_short |
Demystifying lanthanomes: a pangenomic approach |
| title_full |
Demystifying lanthanomes: a pangenomic approach |
| title_fullStr |
Demystifying lanthanomes: a pangenomic approach |
| title_full_unstemmed |
Demystifying lanthanomes: a pangenomic approach |
| title_sort |
demystifying lanthanomes: a pangenomic approach |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/21408 |
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AT rafsanrian demystifyinglanthanomesapangenomicapproach |
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