Targeting circular RNA for cardiovascular diseases
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2023
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| Online Zugang: | http://hdl.handle.net/10361/21244 |
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10361-212442023-10-16T06:49:24Z Targeting circular RNA for cardiovascular diseases Sarkar, Deepannita Chowdhury, Namara Mariam Department of Pharmacy, Brac University Cardiovascular diseases (CVDs) Coronary artery disease (CAD) Cerebrovascular disease (CVD) Peripheral artery disease (PAD) Aortic atherosclerosis RNA Human genetics Cardiovascular system--Diseases This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 53-75). Circular RNAs (CircRNAs) are ubiquitous, and covalently closed loop structures. They are single-stranded molecules without free 3′ and 5 ′ ends. CircRNAs have been rapidly gaining momentum as a potential therapy option for a wide range of cardiovascular disorders, including coronary artery disease (CAD), Cerebrovascular disease (CVD), Peripheral artery disease (PAD), and Aortic atherosclerosis. This review explores several critical aspects such as circRNA biogenesis and suggested biogenesis models, circRNA detection and validation methods, circRNA functions, and current therapeutic uses of circRNA technology. To increase efficacy, these advancements are being researched both independently and in combination with other technologies as well. Significant advances may pave the road for circular RNA technology to be successful in treating these diseases, which are currently affecting a big part of the human population. Deepannita Sarkar B. Pharmacy 2023-09-25T07:37:35Z 2023-09-25T07:37:35Z 2022 2022-11 Thesis ID 18346038 http://hdl.handle.net/10361/21244 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 86 pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
English |
| topic |
Cardiovascular diseases (CVDs) Coronary artery disease (CAD) Cerebrovascular disease (CVD) Peripheral artery disease (PAD) Aortic atherosclerosis RNA Human genetics Cardiovascular system--Diseases |
| spellingShingle |
Cardiovascular diseases (CVDs) Coronary artery disease (CAD) Cerebrovascular disease (CVD) Peripheral artery disease (PAD) Aortic atherosclerosis RNA Human genetics Cardiovascular system--Diseases Sarkar, Deepannita Targeting circular RNA for cardiovascular diseases |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Chowdhury, Namara Mariam |
| author_facet |
Chowdhury, Namara Mariam Sarkar, Deepannita |
| format |
Thesis |
| author |
Sarkar, Deepannita |
| author_sort |
Sarkar, Deepannita |
| title |
Targeting circular RNA for cardiovascular diseases |
| title_short |
Targeting circular RNA for cardiovascular diseases |
| title_full |
Targeting circular RNA for cardiovascular diseases |
| title_fullStr |
Targeting circular RNA for cardiovascular diseases |
| title_full_unstemmed |
Targeting circular RNA for cardiovascular diseases |
| title_sort |
targeting circular rna for cardiovascular diseases |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/21244 |
| work_keys_str_mv |
AT sarkardeepannita targetingcircularrnaforcardiovasculardiseases |
| _version_ |
1814308911566553088 |