Study on Salmonella Typhi-Isolation, characterization and immunological studies

This thesis is submitted in a partial fulfillment of the requirement for the degree of Masters of Science in Biotechnology, 2009

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Arefin, K. M. Shamsul
مؤلفون آخرون: Choudhury, Dr. Naiyyum
التنسيق: أطروحة
اللغة:English
منشور في: BRAC University 2010
الوصول للمادة أونلاين:http://hdl.handle.net/10361/207
id 10361-207
record_format dspace
spelling 10361-2072019-09-29T05:45:11Z Study on Salmonella Typhi-Isolation, characterization and immunological studies Arefin, K. M. Shamsul Choudhury, Dr. Naiyyum Department of Mathematical and Natural Science, BRAC University This thesis is submitted in a partial fulfillment of the requirement for the degree of Masters of Science in Biotechnology, 2009 Cataloged from PDF version of thesis report. Includes bibliographical references (page 37-46). Typhoid fever is one of the most common febrile illnesses and its real impact is difficult to estimate because the clinical picture is confused with other febrile infections. Various diagnostic techniques are used for clinical diagnosis of typhoid patients. Unfortunately no technique so far us'P for can be considered as gold standard as a diagnostic tool for typhoid fever. Widal test is widely used in the developing countries for the diagnosis of the typhoid fever; however, Widal test takes a longer time for diagnosis . having high proportion of false positive results which would complicate the treatment. Blood culture technique is limited due to the indiscriminate use of antibiotics and its utility is restricted due to low numbers of bacteria in blood. Antibodies in lymphocyte supernatant (ALS) assay has recently been developed and standardized for the diagnosis aj typhoid fever which is highly sensitive for detection of Salmonella Typhi infection at early stage. Comparison of ALS assay with blood culture and Widal test has been carried out and the method is sensitive and specific. AL$ able to confirm typhoid infection in 52% patients, whereas, blood culture test confirmed 13% and Widal test confirmed 44% patients to be positive on Salmonella Typhi. Using ALS assay typhoid fever was diagnosed and confirmed within 48 hrs of fever. ALS assay can be used for rapid diagnosis of typhoid fever. K. M. Shamsul Arefin M. Biotechnology 2010-09-23T05:09:27Z 2010-09-23T05:09:27Z 2009 2009 Thesis ID 07176005 http://hdl.handle.net/10361/207 en BRAC University thesis are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 51 pages application/pdf BRAC University
institution Brac University
collection Institutional Repository
language English
description This thesis is submitted in a partial fulfillment of the requirement for the degree of Masters of Science in Biotechnology, 2009
author2 Choudhury, Dr. Naiyyum
author_facet Choudhury, Dr. Naiyyum
Arefin, K. M. Shamsul
format Thesis
author Arefin, K. M. Shamsul
spellingShingle Arefin, K. M. Shamsul
Study on Salmonella Typhi-Isolation, characterization and immunological studies
author_sort Arefin, K. M. Shamsul
title Study on Salmonella Typhi-Isolation, characterization and immunological studies
title_short Study on Salmonella Typhi-Isolation, characterization and immunological studies
title_full Study on Salmonella Typhi-Isolation, characterization and immunological studies
title_fullStr Study on Salmonella Typhi-Isolation, characterization and immunological studies
title_full_unstemmed Study on Salmonella Typhi-Isolation, characterization and immunological studies
title_sort study on salmonella typhi-isolation, characterization and immunological studies
publisher BRAC University
publishDate 2010
url http://hdl.handle.net/10361/207
work_keys_str_mv AT arefinkmshamsul studyonsalmonellatyphiisolationcharacterizationandimmunologicalstudies
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