Therapeutic implication of senescent cell elimination in neurodegenerative diseases
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
| Главный автор: | |
|---|---|
| Другие авторы: | |
| Формат: | Диссертация |
| Язык: | English |
| Опубликовано: |
Brac University
2023
|
| Предметы: | |
| Online-ссылка: | http://hdl.handle.net/10361/19377 |
| id |
10361-19377 |
|---|---|
| record_format |
dspace |
| spelling |
10361-193772023-08-09T21:02:26Z Therapeutic implication of senescent cell elimination in neurodegenerative diseases Key, Nasrin Sultana Kabir, Md. Tanvir Department of Pharmacy, Brac University Neurodegenerative diseases Senescent cell Amyloid-β Senolytic Senostatic Nervous system -- Diseases. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 41-53). Neurodegenerative disease is a condition where the function of the brain gets affected due to neuronal death. Still, there is no proper way to cure this disease, but there are some drugs and treatments that can reduce the side effects caused by this disease. Senescent cell elimination is a treatment used to treat neurodegenerative diseases like Alzheimer’s disease (AD), Parkinson’s disease (PD), etc. It has been revealed that senescent cell causes impaired learning, memory loss, etc. Excess production of amyloid precursor protein and amyloid-β (Aβ) also cause impaired learning or memory loss problems, so senescent cells contribute to neurodegenerative diseases. So, eliminating senescent cells is an excellent method or treatment for neurodegenerative diseases. Senolytic drugs are one kind of senescent cell elimination treatment that induces apoptosis in senescent cells, and senostatics is another senescent cell elimination treatment that blocks or stops the proliferation of senescence. Nasrin Sultana Keya B. Pharmacy 2023-08-09T10:32:12Z 2023-08-09T10:32:12Z 2022 2022-03 Thesis ID: 18146013 http://hdl.handle.net/10361/19377 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 53 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Neurodegenerative diseases Senescent cell Amyloid-β Senolytic Senostatic Nervous system -- Diseases. |
| spellingShingle |
Neurodegenerative diseases Senescent cell Amyloid-β Senolytic Senostatic Nervous system -- Diseases. Key, Nasrin Sultana Therapeutic implication of senescent cell elimination in neurodegenerative diseases |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Kabir, Md. Tanvir |
| author_facet |
Kabir, Md. Tanvir Key, Nasrin Sultana |
| format |
Thesis |
| author |
Key, Nasrin Sultana |
| author_sort |
Key, Nasrin Sultana |
| title |
Therapeutic implication of senescent cell elimination in neurodegenerative diseases |
| title_short |
Therapeutic implication of senescent cell elimination in neurodegenerative diseases |
| title_full |
Therapeutic implication of senescent cell elimination in neurodegenerative diseases |
| title_fullStr |
Therapeutic implication of senescent cell elimination in neurodegenerative diseases |
| title_full_unstemmed |
Therapeutic implication of senescent cell elimination in neurodegenerative diseases |
| title_sort |
therapeutic implication of senescent cell elimination in neurodegenerative diseases |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/19377 |
| work_keys_str_mv |
AT keynasrinsultana therapeuticimplicationofsenescentcelleliminationinneurodegenerativediseases |
| _version_ |
1814309139046727680 |