Efficacy and safety of monotherapy and combination therapy of oral minoxidil for androgenetic alopecia: a structured review
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2023
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| Dostęp online: | http://hdl.handle.net/10361/19029 |
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10361-190292023-07-26T21:02:04Z Efficacy and safety of monotherapy and combination therapy of oral minoxidil for androgenetic alopecia: a structured review Jahan, Safrin Talukder, Mesbah Department of Pharmacy, Brac University Androgenetic alopecia Male pattern hair loss Oral minoxidil Spironolactone Dutasteride intralesional microinjection This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 34-36). In both men and women, AGA is a condition where dihydrotestosterone resulting from testosterone attacks hair follicles. OM is an FDA approved antihypertensive vasodilator. OM is an antihypertensive vasodilator authorized by FDA but not authorized for hair loss therapy. Despite this, low-dose oral minoxidil (LDOM) 0.25 to 5 milligram has displayed a favorable safety and effectiveness profile in numerous research studies (Jimenez-Cauhe, Saceda-Corralo et al. 2019, Vano-Galvan,, Pirmez et al., 2021). Oral minoxidil generates hypertrichosis and cardiovascular system (CVS) symptoms according to numerous clinical studies and the FAERS database. On the other hand, several clinical studies show that oral minoxidil in combination with spironolactone or dutasteride intralesional injections has less side effects than monotherapy of OM. As combination therapy data obtained are based on prospective, uncontrolled and open-label observational studies with and short follow-up. Thus, further studies are warranted for the safety and efficacy of combination therapies. Safrin Jahan B. Pharmacy 2023-07-26T07:10:55Z 2023-07-26T07:10:55Z 2022 2022-11 Thesis ID 18346058 http://hdl.handle.net/10361/19029 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 36 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Androgenetic alopecia Male pattern hair loss Oral minoxidil Spironolactone Dutasteride intralesional microinjection |
| spellingShingle |
Androgenetic alopecia Male pattern hair loss Oral minoxidil Spironolactone Dutasteride intralesional microinjection Jahan, Safrin Efficacy and safety of monotherapy and combination therapy of oral minoxidil for androgenetic alopecia: a structured review |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Talukder, Mesbah |
| author_facet |
Talukder, Mesbah Jahan, Safrin |
| format |
Thesis |
| author |
Jahan, Safrin |
| author_sort |
Jahan, Safrin |
| title |
Efficacy and safety of monotherapy and combination therapy of oral minoxidil for androgenetic alopecia: a structured review |
| title_short |
Efficacy and safety of monotherapy and combination therapy of oral minoxidil for androgenetic alopecia: a structured review |
| title_full |
Efficacy and safety of monotherapy and combination therapy of oral minoxidil for androgenetic alopecia: a structured review |
| title_fullStr |
Efficacy and safety of monotherapy and combination therapy of oral minoxidil for androgenetic alopecia: a structured review |
| title_full_unstemmed |
Efficacy and safety of monotherapy and combination therapy of oral minoxidil for androgenetic alopecia: a structured review |
| title_sort |
efficacy and safety of monotherapy and combination therapy of oral minoxidil for androgenetic alopecia: a structured review |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/19029 |
| work_keys_str_mv |
AT jahansafrin efficacyandsafetyofmonotherapyandcombinationtherapyoforalminoxidilforandrogeneticalopeciaastructuredreview |
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1814307735027580928 |