Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment
This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2022.
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Brac University
2023
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10361-189842023-07-24T21:02:02Z Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment Shaikat, Mahdi Mubin Bin Naser, Dr. Iftekhar Department of Mathematics and Natural Sciences, Brac University CRISPR/Cas9 Genome editing Cancer Vectors Onco genes Cancer treatment Gene editing--Technological innovations. Cancer--Treatment This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 54-63). One of the biggest causes of mortality worldwide is cancer. Cancer is one of the most challenging diseases to cure because of its capacity to spread quickly, metastasis, and create diverse tumors as a result of mutagenesis events. The gene editing tool Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems and CRISPR-associated (Cas) enzymes have demonstrated enormous potential in the treatment of genome-based disorders, particularly cancer, due to their great precision and efficiency. CRISPR-Cas systems can find fresh targets for brand new prospective anti-cancer therapies thanks to their capacity to purposefully activate or repress genes. The mechanisms of the various kinds of CRISPR-Cas systems are outlined in this paper. This study also covers a number of additional uses for CRISPR-Cas systems in the realm of cancer, including as diagnostic and therapeutic uses. Mahdi Mubin Shaikat M. Biotechnology 2023-07-24T06:44:54Z 2023-07-24T06:44:54Z 2022 2022-12 Thesis ID: 21176005 http://hdl.handle.net/10361/18984 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 63 pages application/pdf Brac University |
institution |
Brac University |
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Institutional Repository |
language |
English |
topic |
CRISPR/Cas9 Genome editing Cancer Vectors Onco genes Cancer treatment Gene editing--Technological innovations. Cancer--Treatment |
spellingShingle |
CRISPR/Cas9 Genome editing Cancer Vectors Onco genes Cancer treatment Gene editing--Technological innovations. Cancer--Treatment Shaikat, Mahdi Mubin Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment |
description |
This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2022. |
author2 |
Bin Naser, Dr. Iftekhar |
author_facet |
Bin Naser, Dr. Iftekhar Shaikat, Mahdi Mubin |
format |
Thesis |
author |
Shaikat, Mahdi Mubin |
author_sort |
Shaikat, Mahdi Mubin |
title |
Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment |
title_short |
Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment |
title_full |
Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment |
title_fullStr |
Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment |
title_full_unstemmed |
Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment |
title_sort |
prevalence and application of an evolving genome editing tool “crispr/cas system” in cancer research and treatment |
publisher |
Brac University |
publishDate |
2023 |
url |
http://hdl.handle.net/10361/18984 |
work_keys_str_mv |
AT shaikatmahdimubin prevalenceandapplicationofanevolvinggenomeeditingtoolcrisprcassystemincancerresearchandtreatment |
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1814308248697700352 |