Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): A localized drug delivery approach to treat peritoneal carcinomatosis of different origins
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2023
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| 在线阅读: | http://hdl.handle.net/10361/18940 |
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10361-189402023-07-20T21:02:30Z Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): A localized drug delivery approach to treat peritoneal carcinomatosis of different origins Afrin, Sabrina Momtaz, Tanisha Department of Pharmacy, Brac University Pressurized Intraperitoneal Aerosol Chemotherapy PIPAC Peritoneal carcinomatosis Cancer Oncology Drug delivery Intraperitoneal chemotherapy Anti-cancer agents Antineoplastic Combined Chemotherapy Protocols--therapeutic use--Congresses. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 37-52). Pressurized Intraperitoneal Aerosol Chemotherapy or PIPAC has recently gained focus of researchers worldwide in the field of oncology for treating the notorious cancer peritoneal carcinomatosis. The aim of this review was to present a scientific overview of PIPAC for treating peritoneal carcinomatosis of different origins. The methodology of the research was based on reviewing the available scientific literature from reliable online resources. High pressure and aerosol dosage form are utilized in PIPAC to deliver chemotherapy intraperitoneally. Oxaliplatin and a combination of cisplatin followed by doxorubicin are the most frequently administered drugs in PIPAC. PIPAC exerts a high local activity with lower systemic effects. PIPAC has shown substantial tumor regression and efficacy. Some major and frequent minor adverse effects have been identified. Larger clinical trials are needed to clearly define the indications of PIPAC, assess its long-term toxicity, and expand its clinical use in the treatment of peritoneal carcinomatosis. Sabrina Afrin B. Pharmacy 2023-07-20T06:05:13Z 2023-07-20T06:05:13Z 2022 2022-12 Thesis ID: 18146080 http://hdl.handle.net/10361/18940 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 52 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Pressurized Intraperitoneal Aerosol Chemotherapy PIPAC Peritoneal carcinomatosis Cancer Oncology Drug delivery Intraperitoneal chemotherapy Anti-cancer agents Antineoplastic Combined Chemotherapy Protocols--therapeutic use--Congresses. |
| spellingShingle |
Pressurized Intraperitoneal Aerosol Chemotherapy PIPAC Peritoneal carcinomatosis Cancer Oncology Drug delivery Intraperitoneal chemotherapy Anti-cancer agents Antineoplastic Combined Chemotherapy Protocols--therapeutic use--Congresses. Afrin, Sabrina Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): A localized drug delivery approach to treat peritoneal carcinomatosis of different origins |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Momtaz, Tanisha |
| author_facet |
Momtaz, Tanisha Afrin, Sabrina |
| format |
Thesis |
| author |
Afrin, Sabrina |
| author_sort |
Afrin, Sabrina |
| title |
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): A localized drug delivery approach to treat peritoneal carcinomatosis of different origins |
| title_short |
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): A localized drug delivery approach to treat peritoneal carcinomatosis of different origins |
| title_full |
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): A localized drug delivery approach to treat peritoneal carcinomatosis of different origins |
| title_fullStr |
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): A localized drug delivery approach to treat peritoneal carcinomatosis of different origins |
| title_full_unstemmed |
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): A localized drug delivery approach to treat peritoneal carcinomatosis of different origins |
| title_sort |
pressurized intraperitoneal aerosol chemotherapy (pipac): a localized drug delivery approach to treat peritoneal carcinomatosis of different origins |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/18940 |
| work_keys_str_mv |
AT afrinsabrina pressurizedintraperitonealaerosolchemotherapypipacalocalizeddrugdeliveryapproachtotreatperitonealcarcinomatosisofdifferentorigins |
| _version_ |
1814308009067675648 |