Efficacy of Rivastigmine in Alzheimer’s disease- A structured seview
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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| Idioma: | English |
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Brac University
2023
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| Accés en línia: | http://hdl.handle.net/10361/18748 |
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10361-18748 |
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10361-187482023-07-12T21:03:42Z Efficacy of Rivastigmine in Alzheimer’s disease- A structured seview Alim, Abdul Yasmin, Professor Dr. Hasina Department of Pharmacy, Brac University Alzheimer’s disease Rivastigmine Alzheimer’s disease This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 36-40). Rivastigmine is an anti-cholinesterase agent, used to treat mild to moderate dementia of Alzheimer’s disease (AD). Its efficacy and tolerability increase the treatment compliance. This study focused on determining the efficacy of Rivastigmine by reviewing data from the clinical trials. A structured search was conducted through PubMed up to September 2022 to identify randomized controlled trails (RCT) evaluating the efficacy of oral capsule and transdermal patch of Rivastigmine for AD. The efficacy was assessed using the primary end point, Alzheimer's Disease Assessment Scale–Cognitive Subscale (ADAS-cog) and secondary end point, Mini Mental State Examination (MMSE). It was suggested that Rivastigmine capsule 12 mg/d (twice daily) and Rivastigmine patch 9.5 mg/d (Once daily) is the optimal dose for 24 weeks in mild to moderate AD. Though cholinesterase inhibitors have limited activity, Rivastigmine still represents a positive effect for the treatment of AD. Abdul Alim B. Pharmacy 2023-07-12T05:26:28Z 2023-07-12T05:26:28Z 2022 2022-10-30 Thesis ID: 18346011 http://hdl.handle.net/10361/18748 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 40 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Alzheimer’s disease Rivastigmine Alzheimer’s disease |
| spellingShingle |
Alzheimer’s disease Rivastigmine Alzheimer’s disease Alim, Abdul Efficacy of Rivastigmine in Alzheimer’s disease- A structured seview |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Yasmin, Professor Dr. Hasina |
| author_facet |
Yasmin, Professor Dr. Hasina Alim, Abdul |
| format |
Thesis |
| author |
Alim, Abdul |
| author_sort |
Alim, Abdul |
| title |
Efficacy of Rivastigmine in Alzheimer’s disease- A structured seview |
| title_short |
Efficacy of Rivastigmine in Alzheimer’s disease- A structured seview |
| title_full |
Efficacy of Rivastigmine in Alzheimer’s disease- A structured seview |
| title_fullStr |
Efficacy of Rivastigmine in Alzheimer’s disease- A structured seview |
| title_full_unstemmed |
Efficacy of Rivastigmine in Alzheimer’s disease- A structured seview |
| title_sort |
efficacy of rivastigmine in alzheimer’s disease- a structured seview |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/18748 |
| work_keys_str_mv |
AT alimabdul efficacyofrivastigmineinalzheimersdiseaseastructuredseview |
| _version_ |
1814309577974349824 |